1.2 Sinusitis and antibiotics, Part I. Researchers studying the effect of antibiotic treatment for acute sinusitis compared to symptomatic treatments randomly assigned 166 adults diagnosed with acute sinusitis to one of two groups: treatment or control. Study participants received either a 10-day course of amoxicillin (an antibiotic) or a placebo similar in appearance and taste. The placebo consisted of symptomatic treatments such as acetaminophen, nasal decongestants, etc. At the end of the 10-day period, patients were asked if they experienced improvement in symptoms. The distribution of responses is summarized below.3 Self-reported improvement in symptoms No Yes Total Treatment 66 19 85 Group Control 65 16 81 Total 131 35 166

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1.2 Sinusitis and antibiotics, Part I. Researchers studying the effect of antibiotic treatment for acute
sinusitis compared to symptomatic treatments randomly assigned 166 adults diagnosed with acute sinusitis to
one of two groups: treatment or control. Study participants received either a 10-day course of amoxicillin (an
antibiotic) or a placebo similar in appearance and taste. The placebo consisted of symptomatic treatments
such as acetaminophen, nasal decongestants, etc. At the end of the 10-day period, patients were asked if
they experienced improvement in symptoms. The distribution of responses is summarized below.
Self-reported improvement
in symptoms
Yes
No
Total
Treatment
66
19
85
Group
Control
65
16
81
Total
131
35
166
Transcribed Image Text:1.2 Sinusitis and antibiotics, Part I. Researchers studying the effect of antibiotic treatment for acute sinusitis compared to symptomatic treatments randomly assigned 166 adults diagnosed with acute sinusitis to one of two groups: treatment or control. Study participants received either a 10-day course of amoxicillin (an antibiotic) or a placebo similar in appearance and taste. The placebo consisted of symptomatic treatments such as acetaminophen, nasal decongestants, etc. At the end of the 10-day period, patients were asked if they experienced improvement in symptoms. The distribution of responses is summarized below. Self-reported improvement in symptoms Yes No Total Treatment 66 19 85 Group Control 65 16 81 Total 131 35 166
6. Refer to Exercise 1.2 on p.11. We want to test if there is a difference in the improvement rates of sinusitis
symptoms between the treatment and the placebo.
Formulate the null and alternative hypotheses
Calculate the test statistic
Find the P-value
Please check the conditions required to do the test above.
Transcribed Image Text:6. Refer to Exercise 1.2 on p.11. We want to test if there is a difference in the improvement rates of sinusitis symptoms between the treatment and the placebo. Formulate the null and alternative hypotheses Calculate the test statistic Find the P-value Please check the conditions required to do the test above.
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