1. Ampicillin is an antibiotic used to prevent and treat several bacterial infections. Bacampicillin is a derivative of ampicillin (a prodrug) that enhances the oral bioavailability of the parent antibiotics. In the body, Bacampicillin decomposes to release Ampicillin and side products. Provide a mechanism for the following reaction. For simplicity, replace the core structure with R. NH2 Bacampicillin N NH2 S H3O+ Ampicillin OH Η CO2 Η
1. Ampicillin is an antibiotic used to prevent and treat several bacterial infections. Bacampicillin is a derivative of ampicillin (a prodrug) that enhances the oral bioavailability of the parent antibiotics. In the body, Bacampicillin decomposes to release Ampicillin and side products. Provide a mechanism for the following reaction. For simplicity, replace the core structure with R. NH2 Bacampicillin N NH2 S H3O+ Ampicillin OH Η CO2 Η
Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter18: Functional Derivatives Of Carboxylic Acids
Section: Chapter Questions
Problem 18.69P
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