The acyl group is a protecting group for amines which can be deprotected by treatment with sodium hydroxide. Please write mechanisms for both the protection and deprotection steps.
The acyl group is a protecting group for amines which can be deprotected by treatment with sodium hydroxide. Please write mechanisms for both the protection and deprotection steps.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:5. The acyl group is a protecting group for amines which can be deprotected by
treatment with sodium hydroxide. Please write mechanisms for both the protection
and deprotection steps.
NaOH
CH30-H
NH2
protect
deprotect
R
NH2
amine
acetic anhydride
N-acyl amine
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