ACTIVITY 10.6.2Provide what is being asked.1. A patient has an inborn mutation causing the inability toproduce succinate dehydrogenase required for theoxidation of FADH2. Will this person still produce ATP?Explain your answer.2 Mutations in the genes that encode certain mitochondrialproteins are associated with a high incidence of sometype of cancer. How might defective mitochondria lead tocancer?3. How is cytochrome c related to apoptosis?4. Fill in the table belowPathwayNumber of ATP producedfrom one glucose moleculeNumber of H carriersproduced from oneglucose moleculeNADHFADH2GlycolysisKrebsCycleElectronTransportChainTotal ATPProduced

Answer 1. ATP will be produced by other methods such as glycolysis. But the production of ATP will…

Answered: 1. A patient has an inborn mutation…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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The figure below shows an illustration of a mitochondrian. Mustration of a mitochondrion Which of the following best describes the relationship between the structure and function of the mitochondrion? A B с D The shape of the mitochondrion Increases its material-exchange efficiency by maximiz ing its overall volume relative to its surface area. The double-membrane structure of the mitochondrion allows it to maintain its relatively acidic environment in which nutrients can be digested. The folds of the mitochondrion Inner membrane increase its material-exchange effi- ciency by maximizing its surface area relative to its volume. The specific structure of the mitochondrion Inner membrane allows it to correctly guide the folding of proteins into their functional shape.
4. If lots of acetyl-CoA is being formed in the mitochondrial matrix, a particular compound will be exported into the cytosol. a.What compound is this? b. What effect does this compound have on fatty acid synthesis? c. How does the compound produce this effect?
11. Refer to the figure below. нн Н `NH2 NH2 N' N- 2e-+H* R NAD+ NADH NAD+ functions as a coenzyme in many enzyme-catalyzed reactions. The changes that take place in this coenzyme are the same for all of these reactions and are illustrated in the figure. It is likely that, in these reactions, NAD+ functions as an electron acceptor (reducing agent) in redox reactions. functions as an electron donor (oxidizing agent) in redox reactions. functions as a base in acid-base catalytic mechanisms. functions as an electron donor (oxidizing agent) in redox reactions. functions as an electron acceptor (oxidizing agent) in redox reactions. +Z-
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4) What are the different components of the electron transport chain, where are they situated in cells? Write down the ultimate electron donor and acceptor for each component. How is the released free energy immediately stored during each of these oxidation-reduction reactions (as the reactions are executed)?
19. Which of the following is NOT true of the Embden-Meyerhof-Pamas (EMP) pathway? A. Produces a total of four ATP molecules B. Produces one pyruvate C. Produces two molecules of NADH D. The most common pathway in microbes E. Uses two ATP molecules to modify a glucose molecule K
2. Why are some enzymes needed only in the gluconeogenesis pathway and not in the glycolysis pathway? 3. Which one of the following reactions only occurs during gluconeogenesis (i.e., not during glycolysis)? a. 1,3-bisphosphglycerate into 3-phosphoglycerate b. Glucose 6-phosphate into fructose 6-phosphate c. Oxaloacetate into Phosphoenolpyruvate d. Phosphoenolpyruvate into Pyruvate 4. An increase in glucagon levels can a. Promote the degradation of glycogen (i.e., glycogenolysis) b. Occurs during the fasting state (starvation) c. Promotes the synthesis of glycogen d. A and B 5. A high school girl who is self-conscious about her appearance has been fasting for several days to fit into a dress she intentionally bought a size too small for a school dance. Which of her organs/tissues is producing the glucose that is being synthesized through gluconeogenesis? a. Red blood cells b. Muscles C. Liver d. Brain
10. Oxidative Phosphorylation; a. Occurs in which organelle of the cell and in what structure of this organelle? b. Write the names of the enzyme complexes.
4. Which of the following is responsible for initially receiving electrons from glycolysis upon entering the mitochondria with respect to the G-3-P shuttle system? succinate dehydrogenase triose-phosphate dehydrogenase cytochrome-C oxidase cytochrome reductase
Under certain conditions, cytochrome c can trigger apoptosis, or programmed cell death, by activating cytosolic proteins known as caspases (a) Why doesn’t cytochrome c trigger apoptosis in healthy cells? (b) What must happen in order for cytochrome c to activate the caspases?

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