ppt 4340 blood bank or cell stem donation

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D.A. Degree College for Women *

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1020

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Nursing

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Nov 24, 2024

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pptx

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Student name: Student Id: Topic: Stem cell donation faculty professor name: Due date:
Introduction A method where foundational microorganisms looking great (blood-shaping cells) are given to a client to fill in for their own undifferentiated cells, which have been lost because of radiation openness or forceful treatment. The patient's blood or bone marrow, as well as related or irrelevant contributors, may give the solid undeveloped cells. An immature microorganism relocate can be autologous, which utilizes the patient's own foundational microorganisms that have been assembled and saved preceding treatment, allogeneic, which uses juvenile microorganisms from a related or immaterial provider, syngeneic, which usages undifferentiated cells gave by an undefined twin, or rope blood, which uses umbilical string blood gave after a youngster is considered.
Why it's done Bone marrow transfers are lifesaving therapies for individuals with sicknesses like leukemia, lymphoma, different malignant growths or sickle cell paleness. Given blood undifferentiated cells are required for these transfers.
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Risks o Bone marrow donation Bone marrow undifferentiated living beings are assembled from a piece of the pelvic bone under expansive sedation. The most serious bet related with giving bone marrow incorporates the usage and effects of sedation during operation. o Fringe blood undifferentiated organism donation The dangers of this sort of undifferentiated cell gift are negligible. The infusion that expands the quantity of undifferentiated cells in the blood can cause aftereffects, for example, bone torment, muscle throbs, migraine, weariness, sickness and heaving.
How we get ready To give immature microorganisms, converse with our medical services supplier or contact the Public Marrow Contributor Program. This is a governmentally subsidized philanthropic association that keeps a data set of individuals ready to give. Assuming we choose to give, we'll find out about the cycle and potential dangers of giving. To go on with the cycle, a blood or tissue test can be utilized to assist with matching we to somebody who needs an immature microorganism relocate. we'll likewise be approached to sign an assent structure, yet we can alter our perspective whenever.
Method o Bone marrow donation Gathering immature microorganisms from bone marrow is a sort of a medical procedure done in the working room. Sedation is utilized for the methodology to hold benefactors back from feeling torment. Needles are embedded through the skin and into the rear of the pelvic issue that remains to be worked out the marrow out of the bone. This interaction generally requires 1 to 2 hours. o Fringe blood immature microorganism donation For donation of blood immature microorganisms, benefactors get infusions of medicine that are given under the skin (subcutaneously). The medicine expands the quantity of blood immature microorganisms in the circulation system. The medicine is normally begun a few days before donation.
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After the procedure Recuperation times fluctuate contingent upon the individual and kind of gift. Be that as it may, most contributors can get back to their standard exercises inside the space of days to weeks after donation. Conclusion Turning into a contributor is a serious responsibility. It's challenging to foresee the result for somebody who gets the donation. yet it's conceivable our donation can assist with saving a day to day existence.
References o Mayo Clinic Staff. (2022). Blood and bone marrow stem cell donation. https://www.mayoclinic.org/tests-procedures/bone-marrow-donation/about/pac-20393078#:~:tex t=Peripheral%20blood%20stem%20cell%20donation,-For%20donation%20of&text=During%20the%20don ation%2C%20blood%20is,This%20process%20is%20called%20apheresis o Wang,T. et.al., (2020). Donor genetic backgrounds contribute to the functional heterogeneity of stem cells and clinical outcomes. https:// www.ncbi.nlm.nih.gov/pmc/articles/PMC7695629/ o National Cancer institute. Stem cell transplant. https:// www.cancer.gov/publications/dictionaries/cancer-terms/def/stem-cell-transplant
o J,M, Saudi. (2019). Knowledge and attitude towards hematopoietic stem cell transplantation among medical students at Jazan University, Saudi Arabia. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887877 / o Ari, B, Cuperfain. et. al., (2020). Development and evaluation of stem cell collection procedure diagrams to support the education and recruitment of committed stem cell donors. https://onlinelibrary.wiley.com/doi/abs/10.1111/vox.13010 o Jagelaviciute.G, et. al., (2022). Why We Swab: A library of stories in stem cell donation. https:// onlinelibrary.wiley.com/doi/abs/10.1111/trf.17087 o Fingrut,W. et. al., (2017). The Stem Cell Club: a model for unrelated stem cell donor recruitment. https :// onlinelibrary.wiley.com/doi/full/10.1111/trf.14327 o Mayo clinic. (2022). Blood and born marrow stem cell donation. https://www.mayoclinic.org/tests-procedures/bone-marrow-donation/about/pac-20393078
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o Gersten,T. (2022). Bone marrow (stem cell) donation. https://medlineplus.gov/ency/patientinstructions/000839.htm o Cleveland Clinic. (2022). Bone Marrow Donation https://my.clevelandclinic.org/health/treatments/24387-bone-marrow-donation o Hummer, C. et.al., (2016). Automation of cellular therapy product manufacturing: results of a split validation comparing CD34 selection of peripheral blood stem cell apheresis product with a semi- manual vs. an automatic procedure). https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-016-0826-8 o Armand,P. (2014). Validation and refinement of the Disease Risk Index for allogeneic stem cell transplantation. https://ashpublications.org/blood/article/123/23/3664/33201/Validation-and-refinement-of-the-Diseas e-Risk
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