LWA Negative Feedback Smart Card

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University of Wisconsin, Madison *

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235

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Chemistry

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Feb 20, 2024

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docx

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Lucy Schreiber Anat&Phys Negative Feedback Smart Card 1. Definition Negative Feedback is a regulatory mechanism that works to maintain a stable internal environment (homeostasis). It responds to stimuli that counteracts the initial change to return the system to its normal state. 2. Why is this term/concept important to [physiology] generally and to this unit specifically? Negative Feedback is crucial in physiology because it helps maintain homeostasis and the proper functioning of cells, tissues, and organs. It enables the body to respond to changes in the internal and external environment and make adjustments to maintain stability. In the context of learning how the body remains at homeostasis, negative feedback is essential. 3. How does it relate to what we learned in previous units? This is our first unit in this class so it is the foundation of our what we are to learn through the rest of the semester. It is a core concept of what is going on in our bodies and integral to how our bodies function in a healthy way. 4. How would I apply it to explain something or solve a problem? To apply negative feedback to solve a problem you first must identify the system, the stimulus and its corresponding physiological response, then how negative feedback operates in response to this stimulus. So an example of this would be explaining how the body regulates temperature in response to hot environments. This falls under the nervous system, the stimulus is the external

heat, and the response involves cooling systems like sweating. The negative feedback loop in this instance is sensing the temperature increase and then signaling the sweat glands to bring the body temperature down to normal. 5. How would I use it to analyze, evaluate or create something new? You would have to choose a specific system or process to focus on and examine how the feedback loop contributes to the overall function. Evaluate the efficiency of the loop in maintaining homeostasis, and identify potential disruptors that could affect that loop and how it would lead to dysfunction in the system. Then compare this against negative feedback regulation in other systems. Then you can generate innovative applications and engineer solutions for potential dysfunction.

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