W24 201 Lab 2 final

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CHEM 201 Lab 2: Chemistry of Alka-Seltzer Winter 2024 Lab 2: Background & Procedures Do Not Scan Me to Gradescope Page 1 Lab 2: The Chemistry of Alka-Seltzer ® Tablets By completing all parts of this lab, you will observe the reaction between Alka-Seltzer ® and hydrochloric acid under several experimental conditions and use this data to make claims that relate your observations to the molecular scale reaction. You will work and discuss in small groups of approximately 3-4 for this lab, BUT you will individually scan and submit your own completed Lab 2 worksheet one week after your lab date. Submissions are due one week after your lab, at the same time that your lab normally begins. Late deductions are outlined in the Introduction to CHEM 201 PDF in the Lab 1 folder. What laboratory techniques and skills will you practice? Collecting and recording observations Weighing by differences Dilution of standard solutions What chemical concepts will you apply? Stoichiometry of chemical reactions. Relating macroscopic observations to molecular-level changes Visualizing structural transformations using Lewis diagrams What communication and reporting skills will you use? Using a claim-evidence-reasoning framework to explain connections between qualitative observations and quantitative predictions Before your lab... 1. Read through… ü Lab 2 (this document) 2. Complete… ü Pre-lab 2 (D2L quiz) , with a score of 50% or higher ü Questions P1, P2, and P3 in this document – you will need these ideas and values in the lab, so come prepared! The pre-lab quiz is closely related and will help. You will not be allowed to enter the lab if the safety course is incomplete or you have not passed the pre-lab quiz. Contact your TA or lab coordinator if you have issues with either task. If concepts are unclear or new, refer to the course textbook to review them. On your lab day... Wear clothes & footwear that covers any exposed skin below the hem of the lab coat, including your ankles. Bring your lab coat & safety glasses Bring printed copies of... ü Lab 2 ü Lab Manual Appendices Bring a pen (not pencil) and scientific calculator Arrive at least 5-minutes early - you need to find the room and get ready.
CHEM 201 Lab 2: Chemistry of Alka-Seltzer Winter 2024 Lab 2: Background & Procedures Do Not Scan Me to Gradescope Page 2 Course learning outcomes & prerequisite skills This experiment will have you examining the following overarching course outcomes from the CHEM 201 Course Syllabus: OOA Differentiate between a physical and chemical change. OOB Make key observations during an experiment. OOC Use evidence to provide chemically reasonable rationales for statement(s) given or made. OOD Provide visuals required to help with rationales. You will be utilizing prerequisite expected background knowledge from CHEM 20/30: - Solutions - Stoichiometry The course textbook can help refresh your understanding, in the section Review of Background Topics . These are the course learning outcomes that you will engage with: LO 4 Describe and use electronegativity to predict or explain the type of bonding established between two atoms. LO 5 Describe covalent, polar covalent, and ionic bonding. LO 6 Draw and/or recognize valid and complete Lewis diagrams including all non-zero formal charges.
CHEM 201 Lab 2: Chemistry of Alka-Seltzer Winter 2024 Lab 2: Background & Procedures Do Not Scan Me to Gradescope Page 3 Key Safety Information Corrosive Irritant Hydrochloric acid solutions are corrosive. Although the solution used in this lab is quite dilute, you should wash your hands immediately if your skin comes in contact with the solution. It can also be a respiratory or eye irritant and should be treated with care. Always add acids to water when preparing or diluting solutions – this process is exothermic and can result in dangerous splashing water is added directly to concentrated acids. Background information A structure/bonding chemist is interested in examining what is happening on the molecular level. In Experiment 2 you will investigate what happens when you take Alka-Seltzer ® to minimize heartburn. This is related to a reaction you may have observed as a child (reacting vinegar and baking soda to watch it “foam”). Examining in detail how Alka-Seltzer ® reacts would require that you already understand all concepts being taught in this course. At this point in the semester, therefore, you will have to be told some information in advance; specifically what chemical reactions are taking place (equations [ 1 ] and [ 2 ]). NaHCO 3 ( aq ) + HCℓ ( aq ) H 2 CO 3 ( aq ) + NaCℓ ( aq ) [1] H 2 CO 3 ( aq ) H 2 O ( ) + CO 2 (g ) [2] The sodium bicarbonate (NaHCO 3 ) in Alka-Seltzer ® reacts with hydrochloric acid (HCl) in the stomach to form carbonic acid (H 2 CO 3 ) [ 1 ], which then rapidly breaks down to form carbon dioxide gas (CO 2 ) and water (H 2 O) [ 2 ]. In this procedure, you will react the antacid Alka-Seltzer ® with varying concentrations of hydrochloric acid (to mimic varying levels of stomach acidity). A BALANCED chemical equation demonstrates atom conservation (i.e. the number and types of atoms at the start of a reaction are the same as the number and types of atoms at the end). The stoichiometry of the BALANCED chemical reaction tells one about the ratio of reactants to each other and to the products formed. Lewis diagrams can be used to represent the bonding in a chemical species, and curved arrows can be used to show the electron movement related to the bond-breaking and bond- making that occurs when products are formed. The curved arrow should therefore always start where there is high electron density (e.g. at a bond or lone pair of electrons) and end (i.e. at the arrow head) where those electrons are ending up. It is useful to look at the products and compare with the reactants to understand what bonds are broken or made. Consult the course textbook for more on curly arrows ( link ) Here is an example of the use of curved arrows to show a chemical reaction happening:
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CHEM 201 Lab 2: Chemistry of Alka-Seltzer Winter 2024 Lab 2: Background & Procedures Do Not Scan Me to Gradescope Page 4 When carrying out a chemical reaction in a lab, it is virtually impossible to mix the ideal amounts of reactants as indicated by the stoichiometry of a balanced chemical reaction. One of the reactants is, therefore, measured in excess. As the reaction of Alka-Seltzer ® with hydrochloric acid is an acid-base reaction, pH can be used to determine which reagent is in excess. The reagent not in excess is known as the limiting reagent . Usually, a chemist not only makes qualitative (descriptive) observations like those above but also quantitative (numerical) ones. If reactions [ 1 ] and [ 2 ] are carried out as “open” systems (for example, an Erlenmeyer flask, even if covered by a glass dish), the amount of CO 2 (g) produced can be determined by considering how the weight of the system changes as the gas is released into the lab. For this experiment stoichiometric relationships allow us to relate the amount of CO 2 (g) produced to the amount of NaHCO 3 that reacts. When looking quantitatively at a product made, however, one must be careful that the reactions being studied are the only ones that are occurring. In the case of studying the reaction of Alka-Seltzer ® with hydrochloric acid, is this the only acid-base reaction occurring? You will be asked to calculate the weight percent of sodium bicarbonate in the Alka Seltzer tablet. Weight percent is another unit of concentration ( https://chem-textbook.ucalgary.ca/version2/review- of-background-topics/measurements-and-data/measurements-in-chemistry/other-units-for-solution- concentrations/ ). It is extremely useful to normalize the amount of a component, regardless of the total mass – in this case, the amount of sodium bicarbonate in the total mass of the tablet. In the example below, the two pie-charts represent two different tablets. Note that the weight percent of NaHCO 3 is 25% for both tablets, but the actual amount of NaHCO 3 present is higher in the tablet with a higher total mass. This is why weight percent (% w/w) is a unit of concentration and not a unit of mass or volume. 25 % w/w NaHCO 3 Total mass: 5 g Mass NaHCO 3 : 1.25 g 25 % w/w NaHCO 3 Total mass: 1 g Mass NaHCO 3 : 0.25 g
CHEM 201 Lab 2: Chemistry of Alka-Seltzer Winter 2024 Lab 2: Background & Procedures Do Not Scan Me to Gradescope Page 5 Procedure For this experiment you will work in small groups . Each group member must submit an individually written lab worksheet – all of your observations and conclusions must be in your own words . Take notes in the procedure margins during the lab presentation when your TA provides suggestions of additional cautions or time management tips. Complete all laboratory work in PEN . Before you begin, pick up your group’s equipment tray and check that it contains all of the following items. beaker (6 x 50 mL) Erlenmeyer flasks (6 x 250 mm) graduated cylinder (2 x 50 mL) metal spatula eyedropper permanent marker watch glass (6) test tube brush (medium) beaker (1 x 250 mL) graduated cylinder (1 x 50 mL) Part 1: Preparation of acid solutions for comparison You will make some initial observations about the acid solutions before any reaction takes place, recording your results in Table 1 of your worksheet . 1. Collect approximately 150 mL of 0.60 M aqueous HCl solution in a 250 mL beaker. 2. Ensure your 250 mL Erlenmeyer flasks are clean and dry , and label them A through F. 3. Following Table 1, add the specified amount of Reverse Osmosis (RO) water to each flask, using a graduated cylinder. Use the eyedropper as needed to adjust volumes to the mark on the graduated cylinder. 4. Following Table 1 , next add the specified amount of 0.60 M HCl to each flask, using a graduated cylinder (as in the previous step. 5. Before moving forward, compare values for (A) moles and (B) concentrations of HCl in each flask with your group members. Confirm that the calculated values you each filled in for Table 1 during the pre-lab agree. 6. In Table 1, describe the appearance of the solutions in flasks A-F. 7. Add three drops of Yamada’s Universal Indicator to each of the flasks then cover each flask with a watch glass. In Table 1, describe the appearance of the solutions after the addition of this indicator. 8. Take a minute to make notes as a group on the Reflect and Connect prompt below Table 1 before moving on. Writing some initial thoughts will help you with your post-lab conclusions. ! Warnings: Always add acid to water & not the other way around. HCl solutions are slightly corrosive, please make sure to wash your hands if your skin comes in contact.
CHEM 201 Lab 2: Chemistry of Alka-Seltzer Winter 2024 Lab 2: Background & Procedures Do Not Scan Me to Gradescope Page 6 Part 2: Reaction with Alka-Seltzer® You will track the progress of your reactions both quantitatively (by weighing – Table 2) and qualitatively (visual observations – Table 3). 9. Wipe the outside of each flask A-F with a Kimwipe. Weigh each flask and its contents and record the masses in row 4 of Table 2. 10. Label six 50 mL beakers A to F and add one Alka-Seltzer ® tablet to each. Record the combined mass of each of the six beaker + tablet pairs in Table 2 . Place each beaker in front of the Erlenmeyer flask labelled with the same letters to help stay organized. Now, get ready to record your qualitative observations in Table 3. Make sure that you have a group member ready to track the start time for each flask. 11. When ready, carefully transfer tablet A to flask A. When adding the tablet, hold the flask at an angle to the mouth of the beaker to reduce any splash. Record the time at which the tablet was added and any initial visual observations for flask A. Set Beaker A aside but DO NOT CLEAN IT YET (you still need to re-weigh it!) 12. While the tablet in Flask A continues to react, repeat this process for Flasks B through F, in succession. Make sure to record the start time and any visual observations for each flask, and set each beaker aside without cleaning it. 13. Once all tablets are transferred, re-weigh the beakers used to transfer each tablet and record the masses in Table 2. 14. Calculate the mass of Alka-Seltzer transferred to each flask and record these in Table 2 . 15. Add together your measured initial mass of the flask (with solution and indicator, from Step 9) to the calculated mass of tablet transferred (Step 14) to find the initial total mass at the start of each reaction. Record these masses in Table 2. 16. Swirl each flask gently to ensure complete reaction BUT ALSO AVOID SPILLING ANY SOLUTION . 17. Allow all the tablets to react for approximately 15 minutes ( or until the reaction is complete ). Record all visual observations made during this time in Table 3, including the appearance of the solution, formation of bubbles, presence of undissolved solid, etc. 18. Watch for signs that any of the reactions are complete – if the reaction appears complete, note roughly how many minutes it took to reach completion in Table 3. It should take at most approximately 15 minutes for the reaction to be complete. Describe the visual cues that indicate this reaction has reached completion. 19. Once all reactions have gone to completion, weigh each flask in turn, recording these in Table 2 . IMPORTANT In Lab 1, you learned the importance of weighing by difference. We are using this technique again here – so make sure you weigh the empty beakers after transfer!
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CHEM 201 Lab 2: Chemistry of Alka-Seltzer Winter 2024 Lab 2: Background & Procedures Do Not Scan Me to Gradescope Page 7 20. Now, you will attempt to calculate the %w/w (see Background for more information) from the data you collected for each flask. Use the Sample Calculations page for guidance on the three key calculation steps you need to complete. You will show your work on the Sample Calculations page for Flask E only, but fill in Table 2 for all 6 flasks by following the same steps. 21. Clean up all glassware and dispose of solutions properly. If you have time remaining, complete the Reflect and Connect questions below Tables 1, 2, and 3. Waste disposal. Unused HCl solution goes into the designated waste container, and all reaction solutions go down the sink and are rinsed down with water. Before leaving the lab… Dispose of solutions according to appropriate procedures. Clean all glassware in your equipment tray before you return it. Ensure that your TA initials your observations and data in Table 2 and 3. In Table 2, you must at least have completed all values for Flask E . Ideally, completing all calculations in the lab period saves you work later, and ensures that you have TA support on-hand if you get stuck. We also strongly encourage you to discuss all 3 reflect and connect prompts with your group and make point form notes before you leave. These prompts are designed to kickstart your thinking about key features that you will write about in your analysis after the lab.
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CHEM 201 Lab 2: Chemistry of Alka-Seltzer Winter 2024 Lab 2: Worksheet SCAN & SUBMIT THIS PAGE Page 9 of 16 CHEM 201 Lab 2 Activity Worksheet Your full name UCID # Group members’ names (one name per box): Write all answers in ink in the boxes provided . Any work written outside of the boxes cannot be graded. Submit all 8 worksheet pages as a single document (Page 9-16). Due Date Note: Your report is due one week after the start of your lab session as a Gradescope Assignment. See D2L for further instructions about submission. Academic Integrity Note : You are expected to complete this report working by yourself. You should use your own data, and you may consult the lab manual, lab appendices, lecture notes, course textbook and your TA. Tip for success: Please make sure you understand your results before you leave the lab, since your TA is there to help support you during this time. While you can reach out later, it’s often easier to ask questions when the information is fresh and you can discuss in-person. You can handwrite or type your answers to the Analysis and Discussion section, but your submission must include the scanned original pages from the in-lab observations, with your TA’s initials.
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CHEM 201 Lab 2: Chemistry of Alka-Seltzer Winter 2024 Lab 2: Worksheet SCAN & SUBMIT THIS PAGE Page 10 of 16 Pre-lab preparation Completed before attending your in-person laboratory session As part of your pre-lab quiz on D2L, you were asked questions about the reaction you will study in the lab. Use the feedback received on your quiz to fill-in your answers below before arriving at your lab. P1. Write out the overall balanced chemical equation for the reaction you expect to occur when an Alka-Seltzer tablet is added to a solution of hydrochloric acid. Remember: A complete chemical equation includes the states of all chemical species involved. P2. The separate steps ([ 1 ] and [ 2 ]) that resulted in the overall reaction may give insight into the reaction mechanism or the structural transformations that lead to the products. Lewis diagrams and curved arrows are used to visualize the transformations. (a) Complete the skeletons below to show the “best” Lewis diagrams for the reactants and products of each step. Include all missing lone pairs, bonds, and formal charges . (b) Use curved arrows to show the movement of electrons and show the bonds made and broken in each step. Hint: Can the changes in lone pairs and bonds help you decide where to draw an arrow? [1] [2] P3. Complete rows 5A and 5B of Table 1 on the next page by calculating the different amounts of HCl in each reaction flask A-F, as prepared in Steps 3-4 of the procedure. Two columns have been completed for you, and you will have been asked about another column in your D2L pre-lab quiz.
CHEM 201 Lab 2: Chemistry of Alka-Seltzer Winter 2024 Lab 2: Worksheet SCAN & SUBMIT THIS PAGE Page 11 of 16 In-lab: Data & Initial Reflections Table 1: Qualitative observations of diluted acid solutions Step Flask A Flask B Flask C Flask D Flask E Flask F 3 Volume of water (mL) 35 25 20 10 5 0 4 Volume of 0.60 M HCl stock solution (mL) 0 10. 15 25 30. 35 5A Calculated before lab (pre-lab quiz) Moles of HCl (mol) 0 0.018 5B Calculated before lab (pre-lab quiz) Concentration of HCl (M) 0 0.51 6 Visual appearance of each flask before addition of universal indicator 7 Visual appearance of each flask after addition of universal indicator TA initials here Reflect and connect – Group Notes Solution pH can be related to the colour of the Yamada’s Universal indicator you added – the diagram at the right shows the approximate colour expected for a given solution pH value (along the bottom). With your group, make brief POINT-FORM notes on what combining this new information with your observations ( evidence ) will allow you to claim about the relationship between solution pH and HCl concentration.
CHEM 201 Lab 2: Chemistry of Alka-Seltzer Winter 2024 Lab 2: Worksheet SCAN & SUBMIT THIS PAGE Page 12 of 16 Table 2: Quantitative observations made in the Alka-Seltzer® fizzing experiment. Note how the sequence of table rows follows the procedure. Rows 3-5 should be identical to Table 1 and are repeated for easier reference. Step Flask A Flask B Flask C Flask D Flask E Flask F 3 Volume of water (mL) 35 25 20 10 5 0 4 Volume of 0.60 M HCl stock solution (mL) 0 10. 15 25 30. 35 5A Calculated before lab (copied from Table 1) Moles of HCl (mol) 0 0.018 9 Mass of Flask and HCl Solution with pH indicator (g) 10 Mass of Tablet + Beaker (g) As you add each tablet to its matching flask, you’ll record your observations in Table 3. 13 Mass of empty beaker (g) Weighed after tablets added to flasks 14 Calculated: Mass of tablet transferred (g) 15 Calculated: Total Mass of tablet + flask + HCl Solution + pH indicator (g) 19 Mass of Flask and Contents after Reaction Completion (g) 20 Calculated: Mass of CO 2 lost (g) Calculated: Mass of NaHCO 3 reacted (g) Calculated: % w/w NaHCO 3 in tablet (NaHCO3 weight / tablet weight x 100%) TA initials here Reflect and connect – Group Notes In your group, make brief POINT-FORM notes about this question: Which row(s) in this table allow you to determine which flasks contained excess HCl? Are there other visual cues that indicate excess HCl?
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CHEM 201 Lab 2: Chemistry of Alka-Seltzer Winter 2024 Lab 2: Worksheet SCAN & SUBMIT THIS PAGE Page 13 of 16 Table 3: Qualitative observations made in the Alka-Seltzer® fizzing experiment Remember to be precise in your descriptions – if you say “it was red” do you mean the solution, the solid, or something else? If two boxes of observations are the same, use an arrow to duplicate a description. Flask Reaction start time Observations during the experiment Time to completion (min) Observations once the experiment was complete (or after 15 min) A B C D E F TA initials here Reflect and connect – Group Notes In POINT FORM: What visual cues did your group use to tell if a reaction had reached completion?
CHEM 201 Lab 2: Chemistry of Alka-Seltzer Winter 2024 Lab 2: Worksheet SCAN & SUBMIT THIS PAGE Page 14 of 16 Sample calculations Show your work or process steps for the following calculations for Flask E only. For all other flasks, you will repeat the same process, so you do not need to show your work – simply write your final answers into Table 1. Sample calculation – Mass of CO 2 (g) lost in Flask E Sample calculation – Use your balanced chemical equation, a periodic table (Appendix D), and your mass of CO 2 lost to calculate the mass of NaHCO 3 used or reacted in Flask E. Sample calculation – Use your measured mass of the tablet added to flask E and your calculated mass of NaHCO 3 reacted to determine the %w/w of NaHCO 3 in the tablet added to flask E.
CHEM 201 Lab 2: Chemistry of Alka-Seltzer Winter 2024 Lab 2: Worksheet SCAN & SUBMIT THIS PAGE Page 15 of 16 Analysis & Discussion Completed after laboratory session Use your group notes and observations to reflect back on the laboratory experiment and individually answer all of the following questions. a. Use your group notes below Table 1 to write your own C-E-R argument for this question. CLAIM (argument). Answers the question: Based on your observations, how are pH and HCl concentration related? EVIDENCE (Concrete observations made or data gathered in lab) REASONING E xplain why your observations supports your claim. This explanation reasoning is also where you can incorporate necessary supporting information (like the Yamada indicator scale) b. Using only the data collected in lab , explain which flasks had an excess of HCl (i.e. where NaHCO 3 was the limiting reactant)? Use your group notes below Table 2 to help you. CLAIM (argument). Answers the question: Which flask(s) contained excess HCl? EVIDENCE (must include BOTH Qualitative observations and Quantitative values) REASONING E xplain why your observations supports your claim. You might refer back to your previous claim for support.
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CHEM 201 Lab 2: Chemistry of Alka-Seltzer Winter 2024 Lab 2: Worksheet SCAN & SUBMIT THIS PAGE Page 16 of 16 c. Which flask or flasks’ data can be used to meaningfully (or correctly) calculate the %w/w of NaHCO 3 in an Alka-Seltzer tablet? Explain why. CLAIM (argument). Answers the question: Which flask(s) can be used to calculate %w/w? EVIDENCE Observations or prior claims from (a) and (b). In this case, you are welcome to use your previous claims as part of your evidence – we can build more complex arguments this way! REASONING E xplain why your evidence supports your claim. Remember: The document “Introduction to CHEM 201 Labs” contains additional support on how to make a strong CER argument. You can find this resource on D2L > Labs > Lab 1.