PhysioEx Exercise 2 Activity 5
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PhysioEx Exercise 2 Activity 5
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PhysioEx Lab Report
Exercise 2: Skeletal Muscle Physiology
Activity 5: Fatigue in Isolated Skeletal Muscle
Name: Miranda Daniel
Date: 15 December 2023
Session ID: session-784c4767-7223-dcc8-02d6-78e782e2d840
Pre-lab Quiz Results
You scored 100% by answering 4 out of 4 questions correctly.
Experiment Results
Predict Question
When skeletal muscle twitches fuse so that the peaks and valleys of each
twitch become indistinguishable from each other, the muscle is in a state
known as
You correctly answered: complete (fused) tetanus.
1
When the stimulus frequency reaches a value beyond which no further
increase of skeletal muscle force can occur, the muscle has reached its
You correctly answered: maximal tetanic tension.
2
A decline in a muscle's ability to maintain a constant level of force, or
tension, after prolonged, repetitive stimulation is called
You correctly answered: fatigue.
3
Which of the following is not
thought to be a contributing factor to the
development of fatigue?
You correctly answered: buildup of Ca
in the muscle fibers.
4
2+
12/15/23, 12:11 AM
PhysioEx Exercise 2 Activity 5
https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex2/act5/
2/5
Stop & Think Questions
Experiment Data
Voltage (v)
Stimuli/sec
Rest Period
(sec)
Active Force
Sustained
Maximal
Force (sec)
8.5
120
0
5.86
0.08
8.5
120
0
5.86
0.08
8.5
120
12
5.86
0.02
8.5
120
22
5.86
0.06
Predict Question: If the stimulator is briefly turned off for defined periods
of time, what will happen to the length of time that the muscle is able to
sustain maximal developed tension when the stimulator is turned on
again?
Your answer: The length of the rest period will not substantially impact
the length of time for sustained muscle tension.
1
Why does the stimulated muscle force begin to decrease over time
despite the maintained stimuli? (Note that a decrease in maximal force
indicates muscle fatigue is developing.)
You correctly answered: More than one of these answers could be
correct.
1
Why did the length of the intervening rest period affect the length of time
the skeletal muscle can maintain maximum tension once the stimulator is
turned on again?
You correctly answered: Intracellular concentrations of ADP and P
declined during the rest period.
2
i
12/15/23, 12:11 AM
PhysioEx Exercise 2 Activity 5
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3/5
120 Stimuli/sec at 8.5 V
120 Stimuli/sec at 8.5 V
Post-lab Quiz Results
You scored 100% by answering 5 out of 5 questions correctly.
During cross bridge cycling in skeletal muscle, force is created by the
You correctly answered: power stroke of the myosin heads.
1
The term tetanus refers to
You correctly answered: sustained muscle tension due to repetitive
stimuli.
2
A decline in a muscle's ability to maintain a constant level of force, or
tension, after prolonged, repetitive stimulation is called
3
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PhysioEx Exercise 2 Activity 5
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4/5
Review Sheet Results
You correctly answered: fatigue.
During fatigue
You correctly answered: the number of active cross bridges begins to
decline although the rate of stimulus delivery (frequency) remains
constant.
4
If an intervening rest period is imposed on active skeletal muscle
You correctly answered: the development of fatigue will be delayed.
5
When a skeletal muscle fatigues, what happens to the contractile force
over time?
Your answer:
The force decreases.
1
What are some proposed causes of skeletal muscle fatigue?
Your answer:
High concentration of lactic acid, ADP, and pi.
2
Turning the stimulator off allows a small measure of muscle recovery.
Thus, the muscle will produce more force for a longer time period if the
stimulator is briefly turned off than if the stimuli were allowed to continue
without interruption. Explain why this might occur. How well did the
results compare with your prediction?
Your answer:
If there is more resting time between the stimulations, the muscle has a great period of time it can sustain maximal developed tension. My prediction was correct based on the findings in the experiment.
3
12/15/23, 12:11 AM
PhysioEx Exercise 2 Activity 5
https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex2/act5/
5/5
List a few ways that humans could delay the onset of fatigue when they
are vigorously using their skeletal muscles.
Your answer:
Take longer breaks between workouts, healthy diet, proper body mechanics, hydration, endurance training.
4
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