Assignment - DNA (14 pts.)

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Algonquin College *

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8010

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Biology

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Jan 9, 2024

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docx

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5

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Assignment - DNA (14 pts.) 2 points/question 14 points total Review: Where is the DNA? DNA is packaged, in the nucleus of eukaryotic cells, in chromosomes. In prokaryotic cells chromosomes of DNA are not protected within a nucleus. A chromosome is a single piece of coiled DNA. The DNA is wrapped around histone proteins, like thread wound around a spool. Without histones, the unwound DNA in chromosomes would be very long and potentially disorganized. Each human cell has about 1.8 metres of DNA. Here is a diagram of a chromatid. Each chromosome is made up of two identical chromatids. The centromere is the point where the two sister chromatids touch. Each chromatid has a short arm and a long arm. This is a test diagram. (1) Chromatid. (2) Centromere. (3) Short arm (4) Long arm. Genome
The genome of eukaryotic organisms is the full set of chromosomes in an organism. This is an image of the 46 chromosomes, making up the diploid genome of a human male. 1. How do we know that this is the genome of a male? We know that this is the genome of a male because it contains more Here is a chart that compares the genome sizes of some viruses and organisms. Do you think that humans have the largest genome size? Genome size refers to the number of base pairs (Adenine linked to Thymine; Guanine linked to Cytosine – these are base pairs of DNA). 2. What organism was the first organism to have its genome sequenced? How many base pairs does this organism have? 3. What organism (remember viruses are not organisms) has the smallest genome? How many base pairs?
4. What organism has the largest genome? How many base pairs? 5. How many base pairs are in the human (homo sapiens) genome? 6. What vertebrate organism has the smallest genome? 7. What vertebrate organism has the largest genome? Comparison of different genome sizes Main article:  Genome size Organism type  Organism  Genome size ( base pairs Note  Virus Bacteriophage MS2 3,569 First sequenced RNA-genome [8] Virus SV40 5,224 [9] Virus Phage ?-X174 5,386 First sequenced DNA-genome [10] Virus Phage ? 48,502 Bacterium Haemophilus influenzae 1,830,000 First genome of living organism, July 1995 [11] Bacterium Carsonella ruddii 159,662 Smallest non-viral genome. [12] Bacterium Buchnera aphidicola 600,000 Bacterium Wigglesworthia glossinidia 700,000 Bacterium Escherichia coli 4,600,000 [13] Bacterium Solibacter usitatus  (strain Ellin 6076) 9,970,000 Largest known Bacterial genome Amoeba Amoeba dubia 670,000,000,000 Largest known genome. [14] Plant Arabidopsis thaliana 157,000,000 First plant genome sequenced, December 2000. [15] Plant Genlisea margaretae 63,400,000 Smallest recorded  flowering plant  genome, 2006.
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[15] Plant Fritillaria assyrica 130,000,000,000 Plant Populus trichocarpa 480,000,000 First tree genome, September 2006 Moss Physcomitrella patens 480,000,000 First genome of bryophyte , January 2008  [16] Yeast Saccharomyces cerevisiae 12,100,000 [17] Fungus Aspergillus nidulans 30,000,000 Nematode Caenorhabditis elegans 98,000,000 First multicellular animal genome, December 1998 [18] Nematode Pratylenchus coffeae 20,000,000 Smallest animal genome known [19] Insect Drosophila melanogaster  (fruit fly) 130,000,000 [20] Insect Bombyx mori  (silk moth) 530,000,000 Insect Apis mellifera  (honey bee) 1,770,000,000 Fish Tetraodon nigroviridis  (type of puffer fish) 385,000,000 Smallest vertebrate genome known Mammal Homo sapiens 3,200,000,000 Fish Protopterus aethiopicus  (marbled lungfish) 130,000,000,000 Largest vertebrate genome known Wiki The Human Genome Project If the 3 billion base pairs in the human genome were printed into phone book format, we would have a stack of phone books 170 metres in height. Discovering, or mapping, the human genome sequence was no easy task! The Human Genome Project (HGP) was an international  scientific research  project with a primary goal to determine the sequence of chemical
base pairs which make up  DNA  and to identify and map the approximately 20,000-25,000  genes  of the  human genome . A gene is defined as: a sequence of DNA that specifies the sequence of amino acids in a particular protein. This could be the protein that makes up your eye colour, the protein that makes up the muscle fibres of your heart, the protein that makes up the epithelial cells throughout your body, etc ., etc. The Human Genome Project (HGP) was one of the great feats of exploration in history - an inward voyage of discovery rather than an outward exploration of the planet or the cosmos; an international research effort to sequence and map all of the genes - together known as the genome - of members of our species,  Homo sapiens. Completed in April 2003, the HGP gave us the ability to, for the first time, to read nature's complete genetic blueprint for building a human being. In human DNA there are 3,200,000,000 base pairs organized into 20,000 – 25,000 genes. The exact number of genes encoded by the human genome is still unknown.