The cause and symptom of Down syndrome. Introduction: Humans cell contain 46 chromosome (2n) and are diploid in nature but at the time of fertilization only 23 (n) chromosome is receive by mother and 23 (n) chromosome is receive by father to form a zygote by the process of meiosis. Zygote is formed by the transfer of male gamete (sperm) and female gamete (ova).The ova and sperm are haploid and form a diploid zygote (2n). Zygote receives 46 chromosomes. Some humans are born with abnormalities as they receive abnormal chromosomal number in their cell. Abnormal chromosome is formed when chromosome fails to separate during meiosis and is known as non- disjunction. This nondisjunction causes a trisomy condition called Down syndrome. In which extra set of chromosome is present in chromosome 21 and total chromosome number is 47.

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Chapter 9.4, Problem 2LO

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The cause and symptom of Down syndrome.

Introduction:

Humans cell contain 46 chromosome (2n) and are diploid in nature but at the time of fertilization only 23 (n) chromosome is receive by mother and 23 (n) chromosome is receive by father to form a zygote by the process of meiosis. Zygote is formed by the transfer of male gamete (sperm) and female gamete (ova).The ova and sperm are haploid and form a diploid zygote (2n).

Zygote receives 46 chromosomes. Some humans are born with abnormalities as they receive abnormal chromosomal number in their cell. Abnormal chromosome is formed when chromosome fails to separate during meiosis and is known as non- disjunction. This nondisjunction causes a trisomy condition called Down syndrome. In which extra set of chromosome is present in chromosome 21 and total chromosome number is 47.

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