Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Question
Chapter 9, Problem 8TYU
Summary Introduction
To analyze: ATP that is considered to be an allosteric regulator of phosphofructokinase inhibits or stimulates the activity of this enzyme.
Introduction:
Phosphofructokinase is the most important regulatory enzyme in glycolysis, converting fructose-6 phosphate to fructose-1,6 bisphosphate. Its regulation is allosteric, with adenosine triphosphate (ATP) acting as the allosteric regulator. This enzyme plays a key role in the energy investment step of glycolysis.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Focusing on the mechanism linking complex I and ATP synthase depicted in figure 3 in the article, compare that hypothetical mechanism to the classical presentation described in textbooks. What are the major differences between this mechanism and Peter Mitchel’s original chemiosmotic theory? What are the similarities.
Focusing on the mechanism linking complex I and ATP synthase depicted in figure 3 in the article, compare that hypothetical mechanism to the classical presentation described in our textbook. What are the major differences between this mechanism and Peter Mitchel’s original chemiosmotic theory? What are the similarities.
. In another key reaction in glycolysis, dihydroxyacetone phosphate (DHAP) is isomerized into glyceraldehyde-3-phosphate (GAP) Because ∆G°′ is positive, the equilibrium lies to the left. (a) Calculate the equilibrium constant and the equilibrium fraction of GAP from the above, at 37 °C. (b) In the cell, depletion of GAP makes the reaction proceed. What will ∆G be if the concentration of GAP is always kept at 1/100 of the concentration of DHAP?
Chapter 9 Solutions
Campbell Biology
Ch. 9.1 - Compare and contrast aerobic and anaerobic...Ch. 9.1 - WHAT IF? If the following redox reaction...Ch. 9.2 - Prob. 1CCCh. 9.3 - Prob. 1CCCh. 9.3 - What process in your cells produce the CO2 that...Ch. 9.3 - Prob. 3CCCh. 9.4 - Prob. 1CCCh. 9.4 - WHAT IF? In the absence of O2 as in question 1,...Ch. 9.4 - MAKE CONNECTIONS Membranes must be fluid to...Ch. 9.5 - Consider the NADH formed during glycolysis. What...
Ch. 9.5 - WHAT IF? A glucose-fed yeast cell is moved from...Ch. 9.6 - MAKE CONNECTIONS Compare the structure of a fat...Ch. 9.6 - Prob. 2CCCh. 9.6 - Prob. 3CCCh. 9.6 - Prob. 4CCCh. 9 - Describe the difference between the two processes...Ch. 9 - Which reactions in glycolysis are the source of...Ch. 9 - What molecular products indicate the complete...Ch. 9 - Briefly explain the mechanism by which ATP...Ch. 9 - Prob. 9.5CRCh. 9 - Prob. 9.6CRCh. 9 - Level 1: Knowledge/Comprehension 1. The immediate...Ch. 9 - Prob. 2TYUCh. 9 - Prob. 3TYUCh. 9 - Prob. 4TYUCh. 9 - What is the oxidizing agent in the following...Ch. 9 - When electrons flow along the electron transport...Ch. 9 - Prob. 7TYUCh. 9 - Prob. 8TYUCh. 9 - Prob. 9TYUCh. 9 - Prob. 10TYUCh. 9 - INTERPRET THE DATA Phosphofructokinase is an...Ch. 9 - DRAW IT The graph here shows the pH difference...Ch. 9 - EVOLUTION CONNECTION AIP synthases are found in...Ch. 9 - SCIENTIFIC INQUIRY In the 1930s, some physicians...Ch. 9 - WRITE ABOUT A THEME: ORGANIZATION In a short essay...Ch. 9 - SYNTHESIZE YOUR KNOWLEDGE Coenzyme Q (CoQ) is sold...
Knowledge Booster
Similar questions
- complex 4 cytochrome C oxidase COxidation of one molecule of NADH by the ETC result in transport of 10 protons across the membrane. The c-ring of the ATP synthase in your experimental system contains 12 c subunits. Based on the "binding-change" mechanism of ATP synthesis, how many ATP molecules would be produced from one NADH molecule? n Name the processes that generate NADH during aerobic respiration. For each process, indicate thearrow_forwardHiarrow_forwardWrite a balanced chemical equation for the pentose phosphate pathway in the first two modes depicted as shown, where (a) ribose-5-phosphate synthesis is maximized and (b) NADPH production is maximized, by conversion of the sugar phosphate products to glucose-6-phosphate for repeated operations of the pathway.arrow_forward
- Give typed full explanation Diagram the path of electron flow from NADH to the final electron acceptor during oxidative phosphorylation in mitochondria. For each electron carrier, indicate whether only electrons or both electrons and protons, are accepted/donated by that carrier. B) What would happen to this electron flow and what are the resulting consequences if myxothiazol is added to actively respiring mitochondria using succinate as an electron donor? C) Would you predict ubiquinone reduction to ubiquinol would be more favored at acidic pH or alkaline pH? Why? And as a result, would you predict Complex I active site for this reaction is closer to the N side or P side of the mitochondria?arrow_forward2B. Calculate the total number of ATP that will be generated from the complete B-oxidation of oncobic acid (CH:(CH,),CH=CH(CH,),COOH; 15:1 cis-A9) in an organism that has all the standard required enzymes for metabolism but which pumps only 2 H" in complex I, 0 H' in complex II, 2 H* in complex III and 4 H' in complex IV. The F,F, ATPase is composed of 3 a/ß subunits and 10 c subunits. Show all of your calculations. HOarrow_forwardSome of the biochemical reactions of GLYCOLYSIS are known to have a positive deltaG0, e.g. the cleavage of a 6 carbon compound into two, three-carbon molecules. ONE reason these types of reactions proceed in the forward direction in cells is that... A. hydrogen ions are allowed to flow down their concentration gradient to power the reaction. B. ... NADH is oxidized to NAD+ to power the reaction. C. ... products of the reactions are kept at low concentrations due to their rapid use in downstream reactions with negaive deltaG’s. D. ... ADP is phosphorylated to ATP to power the reaction.arrow_forward
- Predict the effect of each of the following mutations on the pace of glycolysis in liver cells: (a) Loss of the allosteric site for ATP in phosphofructokinase (b) Loss of the binding site for citrate in phosphofructokinase (c) Loss of the phosphatase domain of the bifunctional enzyme that controls the level of fructose 2,6-bisphosphate (d) Loss of the binding site for fructose 1,6-bisphosphate in pyruvate kinasearrow_forwardDraw out the mechanismarrow_forwardEnergy production pathway is targeted by drugs in the malignent cancerous cells to control an x cancer type. Use your speculation and tell targeting and destroying which one energy producing agent of the oxidative phosphorylation will be most effected in blocking most of the energy production and why?arrow_forward
- The following diagram shows reaction curves for aspartate transcarbamoylase (ATCase) with carbamoylphosphate and different concentrations of aspartate, in the absence of ATP (curve 1) and presence of ATP (curve 2). What do the shapes of the curves tell us about the ATCase enzyme? 2 جر [aspartate] It binds substrate through a sequential mechanism. It binds substte cooperatively. It obeys Michaelis-Menten kinetics. It binds substrate through a concerted mechanism.arrow_forwarde 5: The third step of the pathway glycolysis is made up of the two following reactions. i. Fructose-6-phosphate + Pi Fructose 1,6 bisphosphate + H₂O 4Gº' = +16.3 kJ/mol ATP_____+ H₂O → ADP Pi AGO¹ = 30.5 kJ/mol What would be the AGO' for the production of Fructose-6-P and ATP? OAGO' = - 30.5 kJ/mol AGO' AGO' = + 16.3 kJ/mol AGO'= - 14.2 kJ/mol AGO' = 46.8 kJ/mol None of the given answers.arrow_forwardThe AG of the reaction C6H1206+602 --> 6 CO2 + 6H₂O is -686 kcal/mol glucose oxidized. The AG of the reaction ADP + P --> ATP + H₂O is + 7.3 kcal/mol ATP synthesized. The oxidation of glucose can be coupled to the synthesis of ATP. If the coupling is 50% efficient, how many molecules of ATP can be synthesized per molecule of glucose oxidized? Round your answer to the nearest whole number. Type your answer... rces K esc Q 7 c с 72 W #3 E 14 R LL Search or type URL % 65 T G A MacBook Pro 6 Y H & 7 U * 8 + - ( 9 J ၂ ။ K 0 ) 0 L P { + 11 } ] Submit delete returnarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning