Campbell Biology In Focus
2nd Edition
ISBN: 9780134203072
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Textbook Question
Chapter 9, Problem 5TYU
The drug cytochalasin B blocks the function of actin. Which of the following aspects of the animal cell cycle would be most disrupted by cytochalasin B?
- A. spindle formation
- B. spindle attachment to kinetochores
- C. cell elongation during anaphase
- D. cleavage furrow formation and cytokinesis
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Students have asked these similar questions
Which of the following statements about the cell cycle is TRUE?
a. The protein APC blocks cells from entering anaphase
b. CDKs are degraded after each cell cycle phase by the addition of a ubiquitin chain to the proteins
c. A kinase is a protein that adds a ubiquitin chain to other proteins Cyclin activity is necessary, but not always sufficient, for CDK activation
d. Cyclin proteins must be degraded before Cdk proteins can be activated
The diagram below shows a model for the normal regulation of the transition to
anaphase during mitosis.
1. Signals are released by
unattached kinetochores
that cause MAD to bind
CDC20.
MAD
CDC20
6. Chromatids
separate as mitosis
procoeds to anaphase.
COHESIN
3. The APCCDC20
CDC20 complex ubiquinates
Securin.
APC
2. When all kinetochores
are attached, MAD
releases CDC20 which
then combines
with APC
UBIQUITIN
SEPARASE . Separase destroys
Cohesin
APC
SEPARASE
SECURIN
4. Securin is destroyed,
releasing Separase
Your analyses of cancer cells that do not regulate this transition normally indicate that:
MAD is binding to CDC20;
• Ubiquitin is not attached to securin;
• Sister chromatids separate and move to opposite poles of the cell.
Which of the following explanations could account for all of your observations?
a. The cell has an alteration in MAD that prevents it from releasing CDC20 when the 'unattached kinetochore' signal
stops.
O b. More than one of the other answer choices are correct.…
Which of the following statements about mitosis is incorrect?
a. Microtubules from the spindle poles attach to the kinetochores on the chromosomes.
b. In anaphase, the spindle separates sister chromatids and pulls them apart.
c. In metaphase, spindle microtubules align the chromosomes at the spindle midpoint.
d. Cytokinesis describes the movement of chromosomes.
e. Both the animal cell furrow and the plant cell plate form at their former spindle midpoint.
Chapter 9 Solutions
Campbell Biology In Focus
Ch. 9.1 - WHAT IF? A chicken has 78 chromosomes in its...Ch. 9.2 - Compare cytokinesis in animal cells and plant...Ch. 9.2 - Prob. 3CCCh. 9.2 - Compare the roles of tubulin and actin during...Ch. 9.3 - Prob. 1CCCh. 9.3 - Prob. 2CCCh. 9.3 - Compare and contrast a benign tumor and a...Ch. 9.3 - Prob. 4CCCh. 9 - Through a microscope, you can see a cell plate...Ch. 9 - In the cells of some organisms, mitosis occurs...
Ch. 9 - Which of the following does not occur during...Ch. 9 - Prob. 4TYUCh. 9 - The drug cytochalasin B blocks the function of...Ch. 9 - DRAW IT Draw one eukaryotic chromosome as it would...Ch. 9 - The light micrograph shows dividing cells near the...Ch. 9 - SCIENTIFIC INQUIRY Although both ends of a...Ch. 9 - FOCUS ON EVOLUTION The result of mitosis is that...Ch. 9 - SYNTHESIZE YOUR KNOWLEDGE Shown here are two He La...Ch. 9 - FOCUS ON INFORMATION The continuity of life is...
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- What is necessary for a cell to pass the G2 checkpoint? a. cell has reached a sufficient size b. an adequate stockpile of nucleotides c. accurate and complete DNA replication d. proper attachment of mitotic spindle fibers to kinetochoresarrow_forwardWhat celluar events/processes are associated with G1,S,G2,and M phases of the cell cycle? With the phases of mitosis? Some example: A. DNA replication B. Beginning of mitosis C. Normal cell growth and function D. Breaksdown of nuclear membrane E.Separation of sister chromatids F.Alignment of chromosomes on the equator of the cell H.Triggering the compaction and condensation of chromosomes I. Attachment of microtubles to kinetochoresarrow_forwardWhich of the following occurs during metaphase II? A. The chromosomes align midway between spindle poles. B. The sister chromatids separate and move toward the spindle poles. C. Spindle microtubules attach to each sister chromatid as the nuclear envelope breaks up. D. A nuclear envelope forms around each set of chromosomes to form four haploid nuclei.arrow_forward
- Animal cell division is signified by the formation of cleavage furrow as oppose to plant cells, this formation appears at what stage Select one: O a. cytokinesis b. interphase Oc. metaphase O d. prophasearrow_forwardPart of cell division is that chromosomes are moved the center of the cell and then back to the poles of each newly made daughter cell. These chromosomes are moved to the center of the cell by.. Select one: a. Myosin walking on microtubules towards the center of the cell (slow growing end of microtubule) b. Oar-like motion of myosin with microfilaments causing each half of the cell to move closer together c. kinesins walking on microtubules towards the center of the cell (fast growing end of microtubule) d. vesicles floating on microfilaments of the cortical cytoskeletonarrow_forwardIn the mitosis experiment, in what stage were most of the onion root tip cells in? Based on what you know about cell cycle division, what does this imply about the life span of a cell? Were there any stages of the cell cycle that you did not observe? How can you explain this using evidence from the cell cycle?arrow_forward
- Which of the following statements is true of the cell cycle? a The current model of the cell cycle is made up of two main stages. b The cell cycle is a sequential pattern of cell growth, DNA replication, and cell division that takes place in prokaryotic cells. c Knowledge of the cell cycle has remained the same over the last several decades. d The cell cycle is often modeled as a circular diagram, because it is a continuous cycle.arrow_forwardWhich of the following would be expressed at varying levels during different parts of the cell cycle? A. cyclin-dependent kinases B. RNA polymerase C. cyclins D. Glycolysis enzymesarrow_forwardDescribe the role of the following structures or proteins in cell division: a. microtubules b. cohesin protein c. kinetochores d. synaptonemal complexarrow_forward
- The anticancer drug paclitaxel (Taxol), derived from the Pacific Yew, has many effects on mitosis. One of its most powerful effects is that it prevents disassembly of the mitotic spindle, which prevents spindle fibers from shortening. Which phase of mitosis would this directly affect? Why would this stop cell division overall and lead to cell death?arrow_forwardWhich of the following is true of normal adult cells but NOT cancer cells? A. Cell death after a finite number of cell divisions B. Contact with other cells increases likelihood of division C. Large amount of telomerase present D. Do not care about cell density while culturearrow_forwardWith regard to the process of mitosis, which of the following pairs is NOT matched correctly? a. Interphase - the cell grows, chromosomes replicate, and proteins are produced to prepare the cell to divide Ob. Prophase - chromosomes condense, and the nuclear membrane dissociates/breaks down c. Metaphase - chromosomes move toward opposite poles (or sides) of the cell d. Anaphase - sister chromatids separate e. Telophase - two distinct nuclei are formed; this is the stage immediately before cytokinesis O O Oarrow_forward
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