Campbell Essential Biology with Physiology (6th Edition)
6th Edition
ISBN: 9780134711751
Author: Eric J. Simon, Jean L. Dickey, Jane B. Reece
Publisher: PEARSON
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Textbook Question
Chapter 9, Problem 1SQ
The genetic makeup of an organism is called its ______, and the physical traits of an organism are called its _____.
Expert Solution & Answer
Summary Introduction
To analyze: The genetic makeup of an organism and the physical traits of an organism.
Introduction:
The genotype consists of the genes that define the genetic composition of an organism. The phenotype consists of the external visible characteristics of the organism.
Answer to Problem 1SQ
Correct Answer: The genetic makeup of an organism is called its genotype, and the physical traits of an organism are called its phenotype.
Explanation of Solution
The genotype consists of the entire genetic composition of the organism. It includes the genes and their sequences. The phenotype is the external expression of the physical traits of the organism. The examples of genotypes include genes for eye, hair, and nose development. They are the external visible features of the organism. The examples of phenotype include eye color, hair color, and skin color.
Conclusion
The genotype consists of the genetic composition and the genes of the organism. The phenotype consists of the external visible characteristics of the person.
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Kinetics: One-Compartment First-Order Absorption
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.
Using this data and set of graphs, determine:(calculate for each variable)
(a) k, C0, V, and AUC* for the bolus iv data
(b) k, ka, B1, and AUC* for the po data
c) k, ka, B1, and AUC* for the ip data
(d) relative bioavailability for po vs ip, Fpo/Fip
(e)absolute ip bioavailability, Fip
(f) absolute po bioavailability, Fpo
3. A promising new drug is being evaluated in human trials. Based on preliminary human tests, this drug is most effective when plasma levels exceed 30 mg/L. Measurements from preliminary tests indicate the following human pharmacokinetic parameter values: t1/2,elim = 4.6hr, t1/2,abs = 0.34hr, VD = 0.29 L/kg, Foral = 72%. Based on these parameters, estimate the following if a 49 kg woman were to receive a 1000mg oral dose of this drug:
(a) Estimate the plasma concentration of the drug at 1hr, 6 hr, and 20hr after taking the drug ( Concentration estimate)
(b) Estimate the time for maximum plasma concentration (tmax).
(c) Estimate the maximum plasma concentration (Cmax).
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(e)…
Chapter 9 Solutions
Campbell Essential Biology with Physiology (6th Edition)
Ch. 9 - The genetic makeup of an organism is called its...Ch. 9 - Which of Mendels laws is represented by each...Ch. 9 - Prob. 3SQCh. 9 - Prob. 4SQCh. 9 - Prob. 5SQCh. 9 - Prob. 6SQCh. 9 - Prob. 7SQCh. 9 - Prob. 8SQCh. 9 - Prob. 9SQCh. 9 - Prob. 10SQ
Ch. 9 - Prob. 11SQCh. 9 - Prob. 12SQCh. 9 - Incomplete dominance is seen in the inheritance of...Ch. 9 - Why was Henry VIII wrong to blame his wives for...Ch. 9 - Prob. 15SQCh. 9 - Prob. 16SQCh. 9 - Prob. 17SQCh. 9 - Prob. 18IMTCh. 9 - Prob. 19IMTCh. 9 - Prob. 20IMTCh. 9 - Prob. 21PSCh. 9 - Prob. 22PSCh. 9 - Prob. 23BSCh. 9 - Gregor Mendel never saw a gene, yet he concluded...Ch. 9 - Prob. 25BS
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