Concept explainers
a.
To determine: The anticodon for the met (methionine) amino acid.
Introduction: The codon is defined as a sequence of three RNA or DNA bases, which correspond with a specific amino acid. The codon is located on mRNA molecule; whereas, anticodon is located in tRNA molecule.
b.
To explain: The anticodon for trp (tryptophan) amino acid.
Introduction: The codon is defined as a sequence of three RNA or DNA bases, which correspond with a specific amino acid. The codon is located on mRNA molecule; whereas, anticodon is located in tRNA molecule.
c.
To explain: The anticodon for ser (serine) amino acid.
Introduction: The codon is defined as a sequence of three RNA or DNA bases, which correspond with a specific amino acid. The codon is located on mRNA molecule; whereas, anticodon is located in tRNA molecule.
d.
To explain: The anticodon for leu (leucine) amino acid
Introduction: The codon is defined as a sequence of three RNA or DNA bases, which correspond with a specific amino acid. The codon is located on mRNA molecule; whereas, anticodon is located in tRNA molecule.
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Chapter 9 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
- What is meant by the binding problem, and what is necessary for binding to occur?arrow_forwardDiscuss the general structure of the carrier proteins within our cells. Describe how theirstructure allows function.arrow_forwardProtein structure and function: a) Name two common post-translational modifications of proteins in the cell that will affect their structure/function. b) What are prions? Briefly describe their structure and function. C) Explain the principles of protein folding and significance of urea and Bmercaptoethanol in the experimental procedures addressing this question.arrow_forward
- Sickle cell anemia is caused by a point mutation in the β-globin chain of hemoglobin. Glutamic acid is replaced by Valine. HBB sequence in normal adult hemoglobin (Hb A): Leu-Thr-Pro-Glu-Glu-Lys-Ser HBB sequence in mutant adult hemoglobin (Hb S): Leu-Thr-Pro-Val-Glu-Lys-Ser What effect does this mutation have on the structure and function of the protein? Predict what would happen to the RBC if the glutamic acid was replaced with asparagine instead of valine.arrow_forward(b) Hemoglobin is made of B-globin subunits. The first few mRNA nucleotides for B- globin are given by: (1) (iii) (iv) Write down the DNA sequence that has led to this mRNA and indicate the sense and non-sense strands and the polarity. CE Derive the polypeptide for the sequence using the table of the genetic code (Table Q1 below) and indicate the polarity of the polypeptide chain. First Position (5' end) U A single point mutation in mRNA sequence can cause sickle cell anemia by changing the amino acid Glu to Val. For the given mRNA, indicate the point mutations for the first Glu in the polypeptide sequence that can cause this disease. 5'-AUGGUCCACCUGACUCCUGAGGAGAAG...UGA-3' C The polypeptide of B-globin contains the amino acid Leu. Write down all the anticodons of the tRNA molecules that can potentially code for Val. Indicate the polarity of the anti-codon. A G Table 1. The Codons of the Genetic Code Second Position U Phe Phe Leu Leu Leu Leu Leu Leu Ile Ile Ile Met-Start Val Val Val…arrow_forwardAssume that the 3 polypeptide strands shown below form a parallel B-sheet. Select amino acids AA1, AA2, and AA3 so that the parallel B-sheet is amphipathic and remains stable. Glu-lle-Asn-AA1-Cys-Val Ser-AA2-GIn-Leu-Lys-Phe Lys-Met-Cys-Leu-AA3-Val O AA1 = Pro, AA2 = Leu, AA3 = lle O AA1 = Val, AA2 = Leu, AA3 = Asn O AA1 = Ala, AA2 = Gly, AA3 = Leu AA1 = Phe, AA2 = Arg, AA3 = Ala O Oarrow_forward
- Consider the following peptide sequence: Lys-Leu-Ile-Cys-Lys What is the net charge of this sequence at physiological pH? a. -2 b. +1 c. 0 d. -1 e. +2arrow_forwardName the enzyme responsible for binding of aminoacid to trna?arrow_forwardDetermine the mechanism and base change(s) which resulted in the alteration of the sequence of a protein product, arg-leu-met-his-trp-ala to: a. arg b. gly-val-met-asp-trp-gly c. arg-leu-met-hisarrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage LearningHuman Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning