An explanation regarding the absence of mutations in the aspartate residue that interacts with the drugs is to be stated. Concept introduction: Mutation is defined as the change in the sequence/order of DNA bases. It occurs due to the introduction of radiation, chemicals, or an internal disorder. Mutation may be caused by a single change in base sequence.

Question

The preferred substrate is T because the enzyme half-saturates at 7.00 mM for T, but requires 28.0 mM for U, and 112 mM for S. b Question Content Area The rate constant k 2 with substrate S is 9.60×107 sec-1, with substrate T, k 2 = 6.00×104 sec-1, and with substrate U, k 2 = 2.40×106 sec-1. Calculate the catalytic efficiency with S, T, and U. Catalytic efficiency with S = Catalytic efficiency with T = Catalytic efficiency with U = Does enzyme A use substrate S, substrate T, or substrate U with greater catalytic efficiency?

Answer 1

Question

Chapter 9, Problem 13P

Interpretation Introduction

Interpretation:

An explanation regarding the absence of mutations in the aspartate residue that interacts with the drugs is to be stated.

Concept introduction:

Mutation is defined as the change in the sequence/order of DNA bases. It occurs due to the introduction of radiation, chemicals, or an internal disorder. Mutation may be caused by a single change in base sequence.

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