Microbiology: An Introduction
Microbiology: An Introduction
11th Edition
ISBN: 9780321733603
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: Benjamin Cummings
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Chapter 8, Problem 2A

Replication of the E. coli chromosome takes 40 to 45 minutes, but the organism has a generation time of 26 minutes. How does the cell have time to make complete chromosomes for each offspring cell?

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What is the end-replication problem? Why, in the absence of telomerase, do the ends of linear chromosomes get progressively shorter each time the DNA is replicated?
Which of the following is NOT correct concerning the initiation of replication in E. coli?   Question 29 options:   A)    It involves a region of the DNA called oriC.   B)    DnaA proteins bind to the DNA to begin separation of the strands.   C)    The strands are initially separated at GC-rich regions of DNA.   D)    Following initial separation, enzymes continue to separate the parental DNA strands around the rest of the chromosome.
Why would chromosomes shorten with each replication cycle in the absence of telomerase?

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Microbiology: An Introduction

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