Microbiology: An Introduction
11th Edition
ISBN: 9780321733603
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: Benjamin Cummings
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Textbook Question
Chapter 8, Problem 2A
Replication of the E. coli chromosome takes 40 to 45 minutes, but the organism has a generation time of 26 minutes. How does the cell have time to make complete chromosomes for each offspring cell?
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Check out a sample textbook solutionStudents have asked these similar questions
What is the end-replication problem? Why, in the absence of telomerase, do the ends of linear chromosomes get progressively shorter each time the DNA is replicated?
Which of the following is NOT correct concerning the initiation of replication in E. coli?
Question 29 options:
A) It involves a region of the DNA called oriC.
B) DnaA proteins bind to the DNA to begin separation of the strands.
C) The strands are initially separated at GC-rich regions of DNA.
D) Following initial separation, enzymes continue to separate the parental DNA strands around the rest of the chromosome.
Why would chromosomes shorten with each replication cycle in the absence of telomerase?
Chapter 8 Solutions
Microbiology: An Introduction
Ch. 8 - Briefly describe the components of DNA, and...Ch. 8 - DRAW IT Identify and mark each of the following on...Ch. 8 - Match the following examples of mutagens. Column A...Ch. 8 - The following is a code for a strand of DNA. a....Ch. 8 - Prob. 5RCh. 8 - Identify when (before transcription, after...Ch. 8 - Which sequence is the best target for damage by UV...Ch. 8 - You are provided with cultures with the following...Ch. 8 - Why are mutation and recombination important in...Ch. 8 - NAME IT Normally a commensal in the human...
Ch. 8 - Nucleoside analogs and ionizing radiation are used...Ch. 8 - Replication of the E. coli chromosome takes 40 to...Ch. 8 - Pseudomonas has a plasmid containing the mer...Ch. 8 - Match the following terms to the definitions in...Ch. 8 - Match the following terms to the definitions in...Ch. 8 - Feedback inhibition differs from repression...Ch. 8 - Bacteria can acquire antibiotic resistance by all...Ch. 8 - Suppose you inoculate three flasks of minimal...Ch. 8 - Plasmids differ from transposons in that plasmids...Ch. 8 - Mechanism by which the presence of glucose...Ch. 8 - The mechanism by which lactose controls the lac...Ch. 8 - Two offspring cells are most likely to inherit...Ch. 8 - Which of the following is not a method of...Ch. 8 - Ciprofloxacin, erythromycin, and acyclovir are...Ch. 8 - HIV, the virus that causes AIDS, was isolated from...Ch. 8 - Human herpesvirus-8 (HHV-8) is common in parts of...
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- How do the linear chromosomes in eukaryotes ensure that its ends are replicated completely?arrow_forwardHow does DNA replication occur in a precise manner to ensure that identical genetic information is put into the new chromatid? See Figures 8.12 and 8.13. FIGURE 8.12 In DNA replication, the two polynucleotide strands uncoil, and each is a template for synthesizing a new strand. A replicated DNA molecule contains one new strand and one old strand. This mechanism is called semiconservative replication. FIGURE 8.13 A close-up look at the process of DNA replication. (a) As the strands uncoil, bases are added to the newly synthesized strand by complementary base pairing with bases in the template strand. The new bases are linked together by DNA polymerase. (b) DNA synthesis can proceed only in the 5 3 direction; newly synthesized DNA on one template strand is made in short segments and linked together by the enzyme DNA ligase.arrow_forwardIn what ways does chromosomal replication in eukaryotes differ from DNA replication in prokaryotes?arrow_forward
- What is the difference from the polymerase used in transcription of mRNA and the polymerase used during DNA replication that occurs in the S Phase of interphase? What isarrow_forwardWhat happens to the ends of linear chromosomes in eukaryotes during replication? How are the ends of eukaryotic chromosomes maintained? What happens when the process goes wrong?arrow_forwardWhen chromatin is treated with non-specific nucleases, what is the length of the resulting pieces of DNAarrow_forward
- It takes 40 minutes to completely replicate the E. coli chromosome, even in an optimally nourished cell. However, bacterial cells can divide as frequently as every 20 minutes. How can cells divide more rapidly, apparently, than their DNA can be copied?arrow_forwardE. coli is severely exposed to UV light and is DNA damaged, but it attempts to replicate its genome. The prophage gets the signal to leave its host’s genome. The ungrateful phage not only leaves its host but lyses it as it leaves. What type of damage will the UV light cause to the E. coli? E. coli can attempt to replicate its damaged genome. What is the name of this type of DNA replication? What is the name of the response that replicates damaged DNA in E. coli? Which is one of the proteins involved in this response? Explain the events leading to the excision of the lambda prophage from the damaged E. coli, specifically, excision from the host’s genome.arrow_forwardSuppose that E. coli synthesizes DNA at a rate of 100,000 nucleotides per minute and takes 40 minutes to replicate its chromosome. (a) How many base pairs are present in the entire E. coli chromosome? (b) What is the physical length of the chromosome in its helical configuration—that is, what is the circumference of the chromosome if it were opened into a circle?arrow_forward
- Cell cultures can be synchronized, or brought into the same phase of the cell cycle, by various means. For example, adding thymidine to a cell culture causes all cells to become arrested early in S phase. What is the mechanism by which thymidine treatment blocks DNA replication?arrow_forwardAs shown, telomerase attaches additional DNA, six nucleotides at a time, to the ends of eukaryotic chromosomes. However, it makes only one DNA strand. Describe how the opposite strand is replicated.arrow_forwardWhen a cell is to divide, its DNA must be replicated (copied). a) Indicate the main participating components and their functions. b) Why is it important that the replication goes right and that relatively few mutations occur during the replication?arrow_forward
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