Chapter 8, Problem 29P

Interpretation Introduction

Interpretation:

The effect of the mutation on the catalytic rate of an enzyme if the binding of the transition state is unaffected is to be stated.

Concept introduction:

The Michaelis-Menten equation relates the concentration of substrate with the velocity of the reaction. A constant which expresses the substrate’s concentration if the velocity of reaction equals half of the maximum velocity of the reaction is known as Michaelis-Menten constant. It is denoted by $K_{\text{M}}$.