Concept explainers
A.
To explain: The single operator site that is most important for repression
Concept introduction: Prokaryotes regulate their genes using operons. Operons control transcription of multiple genes. Lac operon controls the genes that produce enzymes necessary for
B.
To explain: Whether the combinations of operator sites substantially increase repression by the dimeric repressor and the combination of operator sites substantially increase repression by the tetrameric repressor. The reason as to why the two repressors behave differently.
Concept introduction: Prokaryotes regulate their genes using operons. Operons control transcription of multiple genes. Lac operon controls the genes that produce enzymes necessary for metabolism of lactose. The Lac operon includes operator, promoter, repressor and the genes that code for three enzymes required for conversation of lactose to glucose.
C.
To explain: The wild type repressor binds strongly when O3 is present with O1.
Concept introduction: Prokaryotes regulate their genes using operons. Operons control transcription of multiple genes. Lac operon controls the genes that produce enzymes necessary for metabolism of lactose. The Lac operon includes operator, promoter, repressor and the genes that code for three enzymes required for conversation of lactose to glucose.

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Chapter 8 Solutions
MOLECULAR BIOLOGY OF THE CELL
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- Choose a catecholamine neurotransmitter and describe/draw the components of the synapse important for its signaling including synthesis, packaging into vesicles, receptors, transporters/degradative enzymes. Describe 2 drugs that can act on this system.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. a) Which has a higher potency? b) Which is has a higher efficacy? c) What is the approximate Kd of capsaicin in uM? (you can round to the nearest power of 10)arrow_forwardWhat is the rate-limiting-step for serotonin synthesis?arrow_forward
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