Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Chapter 7, Problem 8IQ
Summary Introduction
To determine: The way by which exchange of sodium ions for potassium ions generate a membrane potential in sodium-potassium pump.
Introduction: The energy-dependent process where the molecules are moved from a region of lower concentration to a region of higher concentration against their concentration gradient is called as active transport. A best example for active transport is the sodium–potassium ATPase pump.
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If a cell with the following ion concentrations had a resting membrane potential of -40mV which of the following can you conclude?
Extracellular: Cl- = 110 mM, Na+ = 145 mM, K+ = 5mM.
Intracellular Cl- = 20 mM, Na+ = 10 mM, K+ = 140mM
a) At rest it is only permeable to potassium
b) At rest it has some permeability to more than one of these ions
c) At rest it is only permeable to chloride
d) Rest it is not permeable to sodium
What is the free energy change for the transport of calcium ions (Ca++) across a membrane from a region (left) where the concentration is 50 micromolar to a region (right) where the concentration is 50 micromolar? A membrane potential of 60 mV exists across the membrane where the right side is more negative than the left side. The temperature is 25 C.
The resting membrane potential is established by?
The Na+/K+-ATPase pumping Na+ into the cell and K+ out of the cell
The Na+/K+-ATPase pumping K+ into the cell and Na+ out of the cell
A larger diffusion of K+ out of the cell compared to diffusion of Na+ into the cell
A larger diffusion of K+ into the cell compared to diffusion of Na+ out of the cell
a) and d)
b) and c)
Chapter 7 Solutions
Study Guide for Campbell Biology
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Assume that a membrane permeable to Na+ but not to Cl- separates two solutions. The concentration of sodium chloride on side 1 is higher than on side 2. Which of the following ionic movements would occur? a. Na+ would move until its concentration gradient is dissipated (until the concentration of Na+ on side 2 is the same as the concentration of Na+ on side 1). b. Cl- would move down its concentration gradient from side 1 to side 2. c. A membrane potential, negative on side 1, would develop. d. A membrane potential, positive on side 1, would develop. e. None of the preceding is correct.arrow_forwardBatrachotoxin (BTX) is a steroidal alkaloid from the skin of Phyllobates terribilis , a poisonous Colombian frog (the source of the poison used on blowgun darts). In the presence of BTX, Na+ channels in an excised patch stay persistently open when the membrane is depolarized. They close when the membrane is repolarized . Which transition is blocked by BTX?arrow_forwardHow does the Na+/K+ pump contribute to the development of a membrane potential?arrow_forward
- Jose measures membrane potential in two neighboring cells. He notices that when the membrane potential changes in one cell, the membrane potential of the neighboring cell changes in a similar manner. For example, if one cell hyperpolarizes, the neighboring cell also hyperpolarizes. He concludes the cells are electrically coupled. Which of the following is the most likely to cause the electrical coupling? a.) The electrical coupling is most probably due to integrins that connect the two cells. b.) The electrical coupling is most probably due to tight junctions that connect the two cells. c.) The electrical coupling is most probably due to desmosomes that connect the two cells. d.) The electrical coupling is most probably due to gap junctions that connect the two cells.arrow_forwardWhat is the equilibrium membrane potential due to Na+ ions if the extracellular concentration of Na+ ions is 154 mM and the intracellular concentration of Na+ ions is 23 mM at 20 ∘C ?arrow_forwardHow do you do this?arrow_forward
- The normal concentrations for intracellular and extracellular potassium in a neuron are [K+]in = 150 mM and [K+]out = 5 mM, respectively. Due to an electrolyte imbalance, a patient has the following intracellular and extracellular concentrations of potassium: [K+]in = 140 mM and [K+]out =2 mM. Using the Nernst equation (Chapter 4), calculate the equilibrium potential for potassium in the cells with normal K+ distributions and of the diseased patient. Refer back to Question #1. Will it be easier or more difficult to generate an action potential in the diseased neuron as compared to the normal neuron? Why?arrow_forwardWhich of the following statements about voltage gated channels is true? Voltage-gated sodium channels open at a higher (more positive) membrane potential than do potassium-gated channels Voltage-gated sodium channels open at a lower (more negative) membrane potential than do potassium-gated channels Sodium- and postassium-gated channels open at about the same membrane potential, but they have different effects because there are different numbers of the two kinds of channels in neuron cell membranesarrow_forwardYou have a semi permeable membrane with a membrane potential of -90mV. You also have two ions that are both permeable to the membrane, Na and Cl. Na has a concentration of 10mM inside the membrane and 120mM outside the membrane. Cl has a concentration of 1.5mM inside the membrane and 77.5mM outside the membrane. Use the nernst equation to calculate the electrochemical equilibrium of both ions, and show in which direction the netflux would be for each ion.arrow_forward
- How can the resting membrane potential of a membrane be calculated using the Goldman-Hodgkin-Katz (GHK) equation?arrow_forwardThe extracellular concentration of Cl-Cl¯ is 123 mM and the intracellular concentration is 4 mM. In which direction does Cl-CI¯| flow through an open channel when the membrane potential is in the -60 mV-60 mV to +30 mV+30 mV range?arrow_forwardWhich statement is TRUE regarding the Na+ voltage-gated channel in neurons? A) Similar to the potassium ion channel, it exists as a tetramer in the membrane. B) Aspartate residues are part of the voltage-sensing helices. C) Positive membrane potentials on the extracellular side will close the channel. D) Ion specificity comes from the voltage-sensing helices.arrow_forward
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