Genetics: From Genes to Genomes, 5th edition
Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 7, Problem 6P

Suppose you wanted to study genes controlling the structure of bacterial cell surfaces. You decide to start by isolating bacterial mutants that are resistant to infection by a bacteriophage that binds to the cell surface. The selection procedure is simple: Spread cells from a culture of sensitive bacteria on a petri plate, expose them to a high concentration of phages, and pick the bacterial colonies that grow. To set up the selection you could (1) spread cells from a single liquid culture of sensitive bacteria on many different plates and pick every resistant colony; or (2) start many different cultures, each grown from a single colony of sensitive bacteria, spread one plate from each culture, and then pick a single mutant from each plate. Which method would ensure that you are isolating many independent mutations?

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Chapter 7 Solutions

Genetics: From Genes to Genomes, 5th edition

Ch. 7 - Remember that balancer chromosomes prevent the...Ch. 7 - In the experiment shown in Fig 7.13 on p. 218, H....Ch. 7 - Figure 7.14 on pp. 219-220 shows examples of base...Ch. 7 - So-called two-way mutagens can induce both a...Ch. 7 - In 1967, J. B. Jenkins treated wild-type male...Ch. 7 - Aflatoxin B1 is a highly mutagenic and...Ch. 7 - When a particular mutagen identified by the Ames...Ch. 7 - Prob. 18PCh. 7 - The Ames test uses the reversion rate his-/i to...Ch. 7 - In human DNA, 70 of cytosine residues that are...Ch. 7 - Albinism in animals is caused by recessive...Ch. 7 - Imagine that you caught a female albino mouse in...Ch. 7 - Plant breeders studying genes influencing leaf...Ch. 7 - In humans, albinism is normally inherited in an...Ch. 7 - Prob. 25PCh. 7 - a. You have a test tube containing 5 ml of a...Ch. 7 - Prob. 27PCh. 7 - The rosy ry gene of Drosophila encodes an enzyme...Ch. 7 - Prob. 29PCh. 7 - In a haploid yeast strain, eight recessive...Ch. 7 - The pathway for arginine biosynthesis in...Ch. 7 - In corn snakes, the wild-type color is brown. One...Ch. 7 - In a certain species of flowering plants with a...Ch. 7 - Prob. 34PCh. 7 - In each of the following cross schemes, two...Ch. 7 - Prob. 36PCh. 7 - The following complementing E. coli mutants were...Ch. 7 - In 1952, an article in the British Medical Journal...Ch. 7 - Mutations in an autosomal gene in humans cause a...Ch. 7 - Antibodies were made that recognize six proteins...Ch. 7 - Prob. 41PCh. 7 - Prob. 42PCh. 7 - In addition to the predominant adult hemoglobin,...Ch. 7 - Prob. 44PCh. 7 - Humans are normally trichromats; we have three...
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