Genetics: From Genes to Genomes, 5th edition
Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 7, Problem 16P

Aflatoxin B1 is a highly mutagenic and carcinogenic compound produced by certain fungi that infect crops such as peanuts. Aflatoxin is a large, bulky molecule that chemically bonds to the base guanine (G) to form the aflatoxin-guanine “adduct” that is pictured below. (In the figure, the aflatoxin is orange, and the guanine base is purple.) This adduct distorts the DNA double helix and blocks replication.

a. What type(s) of DNA repair system is (are) most likely to be involved in repairing the damage caused by exposure of DNA to aflatoxin B1?
b. Recent evidence suggests that the adduct of guanine and aflatoxin B1 can attack the bond that connects it to deoxyribose; this liberates the adducted base, forming an apurinic site. How does this new information change your answer to part (a)?

Chapter 7, Problem 16P, Aflatoxin B1 is a highly mutagenic and carcinogenic compound produced by certain fungi that infect

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After you feel comfortable with your counting method and identifying cells in the various stages of mitosis, use the four images below of whitefish blastula to count the cells in each stage until you reach 100 total cells, recording your data below in Data Table 1. (You may not need to use all four images. Stop counting when you reach 100 total cells.) After totaling the cells in each stage, calculate the percent of cells in each stage. (Divide total of stage by overall total of 100 and then multiply by 100 to obtain percentage.)   Data Table 1Stage    Totals    PercentInterphase        Mitosis:        Prophase        Metaphase        Anaphase        Telophase        Cytokinesis        Totals    100    100% To find the length of time whitefish blastula cells spend in each stage, multiply the percent (recorded as a decimal, in other words take the percent number and divide by 100) by 24 hours. (Example: If percent is 20%, then Time in Hours = .2 * 24 = 4.8) Record your data in Data…
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Chapter 7 Solutions

Genetics: From Genes to Genomes, 5th edition

Ch. 7 - Remember that balancer chromosomes prevent the...Ch. 7 - In the experiment shown in Fig 7.13 on p. 218, H....Ch. 7 - Figure 7.14 on pp. 219-220 shows examples of base...Ch. 7 - So-called two-way mutagens can induce both a...Ch. 7 - In 1967, J. B. Jenkins treated wild-type male...Ch. 7 - Aflatoxin B1 is a highly mutagenic and...Ch. 7 - When a particular mutagen identified by the Ames...Ch. 7 - Prob. 18PCh. 7 - The Ames test uses the reversion rate his-/i to...Ch. 7 - In human DNA, 70 of cytosine residues that are...Ch. 7 - Albinism in animals is caused by recessive...Ch. 7 - Imagine that you caught a female albino mouse in...Ch. 7 - Plant breeders studying genes influencing leaf...Ch. 7 - In humans, albinism is normally inherited in an...Ch. 7 - Prob. 25PCh. 7 - a. You have a test tube containing 5 ml of a...Ch. 7 - Prob. 27PCh. 7 - The rosy ry gene of Drosophila encodes an enzyme...Ch. 7 - Prob. 29PCh. 7 - In a haploid yeast strain, eight recessive...Ch. 7 - The pathway for arginine biosynthesis in...Ch. 7 - In corn snakes, the wild-type color is brown. One...Ch. 7 - In a certain species of flowering plants with a...Ch. 7 - Prob. 34PCh. 7 - In each of the following cross schemes, two...Ch. 7 - Prob. 36PCh. 7 - The following complementing E. coli mutants were...Ch. 7 - In 1952, an article in the British Medical Journal...Ch. 7 - Mutations in an autosomal gene in humans cause a...Ch. 7 - Antibodies were made that recognize six proteins...Ch. 7 - Prob. 41PCh. 7 - Prob. 42PCh. 7 - In addition to the predominant adult hemoglobin,...Ch. 7 - Prob. 44PCh. 7 - Humans are normally trichromats; we have three...
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TISSUE REPAIR Part 1: Repair - Regeneration; Author: ilovepathology;https://www.youtube.com/watch?v=t-5EjlS6qjk;License: Standard YouTube License, CC-BY