Genetics: From Genes to Genomes, 5th edition
Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 7, Problem 41P
Summary Introduction

a.

To determine:

The number of genes required to define the structure of the hemoglobin protein.

Introduction:

Hemoglobin is a protein present in the red blood cells, which carries oxygen to the body tissues. It forms a reversible and unstable bond with the oxygen atom. Adult hemoglobin consists of a multimeric protein with four polypeptides. Two of the peptides consist of two units of alpha globin, with two units of beta globin.

Summary Introduction

b.

To determine:

The different types of hemoglobin protein that would be found in a person’s red blood cell and their proportion if a person is heterozygous for wild-type alleles and the allele that would yield amino acid substitution for both α-globin and β-globin.

Introduction:

Hemoglobin is a globular protein with a quarternary structure. Hemoglobin contains four globular chains. Each of the globular chains is wrapped around the heme group. Each heme group has iron in it, which gives hemoglobin the ability to bind oxygen atom to it. There are various isoforms of globin. The common isoforms are alpha, beta, gamma, and delta.

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Chapter 7 Solutions

Genetics: From Genes to Genomes, 5th edition

Ch. 7 - Remember that balancer chromosomes prevent the...Ch. 7 - In the experiment shown in Fig 7.13 on p. 218, H....Ch. 7 - Figure 7.14 on pp. 219-220 shows examples of base...Ch. 7 - So-called two-way mutagens can induce both a...Ch. 7 - In 1967, J. B. Jenkins treated wild-type male...Ch. 7 - Aflatoxin B1 is a highly mutagenic and...Ch. 7 - When a particular mutagen identified by the Ames...Ch. 7 - Prob. 18PCh. 7 - The Ames test uses the reversion rate his-/i to...Ch. 7 - In human DNA, 70 of cytosine residues that are...Ch. 7 - Albinism in animals is caused by recessive...Ch. 7 - Imagine that you caught a female albino mouse in...Ch. 7 - Plant breeders studying genes influencing leaf...Ch. 7 - In humans, albinism is normally inherited in an...Ch. 7 - Prob. 25PCh. 7 - a. You have a test tube containing 5 ml of a...Ch. 7 - Prob. 27PCh. 7 - The rosy ry gene of Drosophila encodes an enzyme...Ch. 7 - Prob. 29PCh. 7 - In a haploid yeast strain, eight recessive...Ch. 7 - The pathway for arginine biosynthesis in...Ch. 7 - In corn snakes, the wild-type color is brown. One...Ch. 7 - In a certain species of flowering plants with a...Ch. 7 - Prob. 34PCh. 7 - In each of the following cross schemes, two...Ch. 7 - Prob. 36PCh. 7 - The following complementing E. coli mutants were...Ch. 7 - In 1952, an article in the British Medical Journal...Ch. 7 - Mutations in an autosomal gene in humans cause a...Ch. 7 - Antibodies were made that recognize six proteins...Ch. 7 - Prob. 41PCh. 7 - Prob. 42PCh. 7 - In addition to the predominant adult hemoglobin,...Ch. 7 - Prob. 44PCh. 7 - Humans are normally trichromats; we have three...
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