Chapter 6, Problem 6.11P

Interpretation Introduction

(a)

Interpretation:

The line-and-wedge formula of $\left(S\right)\text{-}(+)$-ibuprofen is to be drawn.

Concept introduction:

The naming of the chiral center and geometric isomers are based on Cahn-Ingold-Prelog priority rules. If the priority assigned to each group attached to the chiral center in a molecule is in a clockwise direction, then it is the R-stereoisomer, and if this is counter-clockwise, then it is the S-stereoisomer. R and S-stereoisomer are mirror images of each other.

Interpretation Introduction

(b)

Interpretation:

The specific rotation of pure $\left(S\right)\text{-}(+)$-ibuprofen and pure $\left(R\right)\text{-}(-)$-ibuprofen is to be calculated.

Concept introduction:

A carbon atom that has four nonequivalent atoms or groups attached to it is known as the chiral carbon atom. Chiral carbon centers are also called as asymmetric or stereogenic centers. A chiral molecule is an optically active molecule. It rotates the plane of a plane polarized light. The enantiomeric excess of a sample is given as,

$EE=100\%\times \frac{{\left[\alpha \right]}_{\text{mixture}}}{{\left[\alpha \right]}_{\text{pure}}}$

Interpretation Introduction

(c)

Interpretation:

The percentage of each enantiomer present in the given sample is to be calculated.

Concept introduction:

A carbon atom that has four nonequivalent atoms or groups attached to it is known as the chiral carbon atom. Chiral carbon centers are also called as asymmetric or stereogenic centers. A chiral molecule is an optically active molecule. It rotates the plane of a plane polarized light. The enantiomeric excess of a sample is given as,

$EE=100\%\times \frac{{\left[\alpha \right]}_{\text{mixture}}}{{\left[\alpha \right]}_{\text{pure}}}$