Concepts of Genetics (11th Edition)
11th Edition
ISBN: 9780321948915
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Textbook Question
Chapter 6, Problem 28ESP
For the experiment in Problem 26, another gene, g, was studied. It demonstrated positive cotransformation when tested with gene f. Predict the results of testing gene g with genes a, b, c, d, and e.
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A wild-type mouse that is heterozygous for two immunoglobulin heavy chain alleles (IgHa/b) generates the population of B cells shown on the left of the figure below. A mouse strain, also IgHa/b, carries an inactivating mutation in the VpreB gene. In addition to producing fewer mature B cells than the wild-type mice, the VpreB-deficient mice generate B cells as shown on the right. What is the explanation of the difference seen between the wild-type and the VpreB-mutant B cells?
The following recombinants are recovered when
conjugation occurs between an a*d*g+ donor and an
adg recipient.
at d+ g+ = 84%
a d g+ = 6%
at d g+ = 10%
a dt g+ = less than 1%
What is the map distance between the a and d genes?
10 map units
74 map units
less than 1 map unit
84 map units
6 map units
In the transformation experiment by Griffith, two
strains of an organism was injected into a mouse
model. One, he labelled S was a heat-killed but
pathogenic strain while the other, R was a non-
virulent or non-pathogenic strain. Within 48 hours,
the mouse died and only the S strain was obtained
from the dead mouse. What conclusions can you
derived from this experiment?
A. Some of the pathogenic S strains survived,
proliferated and subsequently overpowered the R strain.
B. The R strains mutated and were converted to a
pathogenic S strain.
C. The R strains assimilated the DNA from the S strain
and were transformed into the S strain.
D. The R strain DNA hybridized with the S strain DNA
such that the daughter DNA of the new generation of R
all contained the S DNA.
E. All of these conclusions are possible.
Chapter 6 Solutions
Concepts of Genetics (11th Edition)
Ch. 6 - When the interrupted mating technique was used...Ch. 6 - In a transformation experiment involving a...Ch. 6 - In complementation studies of the rII locus of...Ch. 6 - Prob. 1CSCh. 6 - Prob. 2CSCh. 6 - Prob. 3CSCh. 6 - Prob. 4CSCh. 6 - HOW DO WE KNOW? In this chapter, we have focused...Ch. 6 - Review the Chapter Concepts list on p. 123. Many...Ch. 6 - With respect to F+ and F bacterial matings, answer...
Ch. 6 - List all major differences between (a) the F+ F...Ch. 6 - Describe the basis for chromosome mapping in the...Ch. 6 - In general, when recombination experiments are...Ch. 6 - Why are the recombinants produced from an Hfr F...Ch. 6 - Describe the origin of F bacteria and merozygotes.Ch. 6 - In a transformation experiment, donor DNA was...Ch. 6 - Describe the role of heteroduplex formation during...Ch. 6 - Explain the observations that led Zinder and...Ch. 6 - Prob. 12PDQCh. 6 - Prob. 13PDQCh. 6 - Two theoretical genetic strains of a virus (abc...Ch. 6 - The bacteriophage genome consists of many genes...Ch. 6 - If a single bacteriophage infects one E. coli cell...Ch. 6 - A phage-infected bacterial culture was subjected...Ch. 6 - In recombination studies of the rII locus in phage...Ch. 6 - In an analysis of rII mutants, complementation...Ch. 6 - If further testing of the mutations in Problem 18...Ch. 6 - Using mutants 2 and 3 from Problem 19, following...Ch. 6 - During the analysis of seven rII mutations in...Ch. 6 - In studies of recombination between mutants 1 and...Ch. 6 - Prob. 24ESPCh. 6 - An Hfr strain is used to map three genes in an...Ch. 6 - A plaque assay is performed beginning with 1 mL of...Ch. 6 - In a cotransformation experiment, using various...Ch. 6 - For the experiment in Problem 26, another gene, g,...Ch. 6 - Bacterial conjugation, mediated mainly by...Ch. 6 - A study was conducted in an attempt to determine...Ch. 6 - Prob. 31ESP
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