EBK HUMAN PHYSIOLOGY
EBK HUMAN PHYSIOLOGY
15th Edition
ISBN: 9781260163049
Author: Fox
Publisher: MCGRAW HILL BOOK COMPANY
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Chapter 6, Problem 22RA
Summary Introduction

To review:

The following:

Cause-and-effect sequence

Symptoms of cystic fibrosis.

Introduction:

Cystic fibrosis is a genetic defect. It is an inherited life-threatening disorder that affects the lungs and the digestive system. The most common mutation which leads to cystic fibrosis is the deletion of the phenylalanine 508. Cystic fibrosis is a recessive disease. A person having a mutation in both copies of the CFTR (cystic fibrosis transmembrane conductance regulator) gene shows cystic fibrosis.

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Alleles at the P locus control seed color. Plants which are pp have white seeds, white flowers and no pigment in vegetative parts. Plants which are P_ have black seeds, purple flowers and may have varying degrees of pigment on stems and leaves. Seed color can be assessed, visually, based on if the seed is white or not white A gene for mold resistance has been reported and we want to determine its inheritance and whether it is linked to P. For the purposes of this exercise, we will assume that resistance is controlled by a single locus M, and M_ plants are resistant and mm plants are susceptible.  Resistance can be measured, under greenhouse conditions, 2 weeks after planting, by injecting each seedling with a spore suspension. After two weeks, the seedlings can be rated as resistant or susceptible, based on whether or not tissue is actively sporulating. For this exercise we will use seed and data from the F10 generation of a recombinant inbred population produced using single seed…

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EBK HUMAN PHYSIOLOGY

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