Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 6, Problem 1ITD
Summary Introduction

To review:

The ∆G for the parent polypeptide and the mutated polypeptide binding to the protein.

Introduction:

The thermodynamics of the polypeptide (a drug) and the PSD-95 is shown in the given graphs. PSD-95 is an important member of the MAGUK (membrane-associated guanylate kinase) family. PSD-95 is an important protein and regulates the nervous system of the mammals. The second law of thermodynamics tells us the amount of Gibbs free energy (∆G) released in the system.

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