Biology (MindTap Course List)
Biology (MindTap Course List)
10th Edition
ISBN: 9781285423586
Author: Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher: Cengage Learning
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Chapter 6, Problem 16TYU
Summary Introduction

To determine: What would be the difficulties of finding cancer drugs that works by inhibiting tyrosine kinase given that similar kinases also function in normal cells.

Introduction: Enzyme-linked receptor is a transmembrane protein with a binding site for signaling molecule outside the cell and an enzyme component inside the cell. An example of enzyme-linked receptor is tyrosine kinase. On binding of ligands with the enzyme-linked receptors, receptor protein comes close together in the plasma membrane and forms dimer which initiates activation of downstream molecules and causes cellular response.

Summary Introduction

To suggest: Whether it could be possible to develop such new medication through government-sponsored research. Why or why not.

Introduction: Enzyme-linked receptor is a transmembrane protein with a binding site for signaling molecule outside the cell and an enzyme component inside the cell. An example of enzyme-linked receptor is tyrosine kinase. On binding of ligands with the enzyme-linked receptors, receptor protein comes close together in the plasma membrane and forms dimer which initiates activation of downstream molecules and causes cellular response.

Summary Introduction

To suggest: Alternatives if it is not possible to develop new such medication through government-sponsored research.

Introduction: Enzyme-linked receptor is a transmembrane protein with a binding site for signaling molecule outside the cell and an enzyme component inside the cell. An example of enzyme-linked receptor is tyrosine kinase. On binding of ligands with the enzyme-linked receptors, receptor protein comes close together in the plasma membrane and forms dimer which initiates activation of downstream molecules and causes cellular response.

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