BIOCHEMISTRY BOOKS ALC&MOD MST/ET PKG
1st Edition
ISBN: 9780134172507
Author: APPLING
Publisher: Pearson Education
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Chapter 6, Problem 15P
It has been postulated that the normal (noninfectious) form of prion differs from the infectious form only in secondary/tertiary structure.
a. How might you show that changes in secondary structure occur?
b. If this model is correct, what are the implications for structural prediction schemes?
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2. For the flow of fluid over a flat membrane of length 10cm,
determine the length-average mass transfer coefficient. The
relevant properties of the system are u=0.01cm²/s, D=5 x 106
cm²/s, and v = 5.0 cm/s.
Background
Freezing isn't the only challenge in cryopreservation - thawing can
be just as difficult. A microwave oven seems like a nice solution,
since it deposits energy quickly and microwaves are non-ionizing
radiation (they do not cause DNA mutation). However, water
absorbs microwaves more effectively than ice does, meaning that
the portion of an organ that has already melted will get warmer at a
higher rate than the remaining ice – the opposite of what we want!
-
The transmission of radiation through a weakly absorbing material
such as ice or water can be modeled by Beer's law, which assumes
that the rate of absorption at a depth x is proportional to the local
radiation intensity I(x) times an absorption coefficient, which is often
written as μ or a or just µ). Noting that absorption decreases the
intensity, we can write a differential equation
a
Solving the differential equation with the boundary condition on the
surface being
gives the relationship
For a standard microwave oven…
3. Dry air is inhaled at a rate of 10 liter/min through a trachea with
a diameter of 20 mm and a length of 125 mm. The inner
surface of the trachea is at a normal body temperature of 37°C
and may be assumed to be saturated with water.
a. Assuming steady, fully developed flow in the trachea,
estimate the mass transfer convection coefficient.
b. Estimate the daily water loss (liter/day) associated with
evaporation in the trachea.
Chapter 6 Solutions
BIOCHEMISTRY BOOKS ALC&MOD MST/ET PKG
Ch. 6 - Prob. 1PCh. 6 - Bovine pancreatic trypsin inhibitor (BPTI; Figure...Ch. 6 - A schematic structure of the subunit of...Ch. 6 - In the protein adenylate kinase, the C-terminal...Ch. 6 - Give two reasons to explain why a proline residue...Ch. 6 - Consider a small protein containing 101 amino acid...Ch. 6 - a. Based on a more conservative answer to Problem...Ch. 6 - The following sequence is part of a globular...Ch. 6 - a. A protein is found to be a tetramer of...Ch. 6 - Under physiological conditions, the protein...
Ch. 6 - Theoretical and experimental measurements show...Ch. 6 - The peptide hormone vasopressin is used in the...Ch. 6 - A protein gives under conditions of buffer...Ch. 6 - A protein gives a single band on SDS get...Ch. 6 - It has been postulated that the normal...Ch. 6 - Prob. 16PCh. 6 - Do you expect a Pro Gly mutation in a...Ch. 6 - Rank the following in terms of predicted rates...
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