BIOCHEMISTRY BOOKS ALC&MOD MST/ET PKG
BIOCHEMISTRY BOOKS ALC&MOD MST/ET PKG
1st Edition
ISBN: 9780134172507
Author: APPLING
Publisher: Pearson Education
bartleby

Concept explainers

bartleby

Videos

Textbook Question
Book Icon
Chapter 6, Problem 7P

a. Based on a more conservative answer to Problem 6 (2.7 x 1092 conformations), estimate the conformational entropy change on folding a mole of this protein into a native structure with only one conformation. (Hint Consider Equation )
b. If the protein folds entirely into a helix with H bonds as the only source of enthalpy of stabilization, and each mole of H bonds contributes -5 kJ/mol to the enthalpy, estimate Δ Hfolding . Note that the ends of helices contain fewer hydrogen bonds per residue than in the middle (see Figure 6.4).
c. From your answers (a) and (b), estimate Δ Gfolding for this protem at 25oC. Is the folded form of the protein stable at 25oC?

6. Consider a small protein containing 101 amino acid residues. The protein backbone win have 200 bonds about which rotation can occur. Assume that three orientations are possible about each these bonds.
a. Based on these assumptions, about how many random-con conformations will be possible for this protein?
b. The estimate obtained in (a) is surety too large. Give one reason why.

Chapter 6, Problem 7P, a. Based on a more conservative answer to Problem 6 (2.7 x 1092 conformations), estimate the , example  1Chapter 6, Problem 7P, a. Based on a more conservative answer to Problem 6 (2.7 x 1092 conformations), estimate the , example  2Chapter 6, Problem 7P, a. Based on a more conservative answer to Problem 6 (2.7 x 1092 conformations), estimate the , example  3

Blurred answer
Students have asked these similar questions
12. When glutamic acid is heated to 180°C., it loses a molecule of water to form a lactam. The bond that creates the lactam is an amide bond that forms between the amino nitrogen and the carbon of the side chain -COOH group. What is the most reasonable structure for this lactam? (NOTE: The structure of glutamic acid is shown in Question 1.) COOH COOH ا کچھ جو کچھ C D COOH B COOH E COOH
10. Which one of the following compounds is the major organic product of the series of reactions shown here? Ph A OH Ph B CO₂Et Br -H Ν ΚΑ CO₂Et 1. NaOEt 1. NaOH, H₂O 2. H3O+ 2. PhCH2CH2Br 3. heat NH2 Ph OH NH2 0 OH Ph OH NH2 Ph D NH2 E OH
1. What is the isoelectric point of glutamic acid? (Glutamic acid has pKa1 2.10, pKa2 4.07, pKaз 9.47) A) pH 2.1 D) pH 6.8 B) pH 3.1 C) pH 4.1 E) pH 9.5 HO NH2 Glutamic acid (shown without charges) OH
Knowledge Booster
Background pattern image
Biochemistry
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Text book image
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Text book image
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Cengage Learning
Text book image
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Text book image
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Text book image
Principles Of Pharmacology Med Assist
Biology
ISBN:9781337512442
Author:RICE
Publisher:Cengage
Biomolecules - Protein - Amino acids; Author: Tutorials Point (India) Ltd.;https://www.youtube.com/watch?v=ySNVPDHJ0ek;License: Standard YouTube License, CC-BY