Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 6, Problem 15CONQ
Researchers have discovered that some regions of chromosomes are much more likely than others to cross over. We might call such a region a “hot spot” for crossing over. Let’s suppose that two genes, gene A and gene B, are
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Researchers have discovered that some regions of chromosomes are more likely than others to cross over, these areas of frequent crossing over are called "recombination hot spots".
Gene A and B are 500,000 bp apart - both genes and the space between them are in a recombination hot spot.
Gene C and D are also 500,000 bp apart but the region containing genes C and D are not a recombination hot spot.
Would the map distance between A and B be the same as the map distance between C and D? Explain your answer.
Can simple translocations ever be balanced?
I know with reciprocal translocations that if you're swapping the same *amount* of genetic material, it would be balanced, but if not, it would probably be unbalanced. (I'm referring to the genetic material of each chromosome, and not the total genetic material).
But simple translocations on the other hand, you're adding part of a chromosome to another without swapping. So it's not possible to have a balanced simple translocation, correct?
How is it still balanced if, let's say we have 100% chromosome A and 100% chromosome B. In simple translocation, 25% of chromosome A moves to chromosome B, to get 125% genetic material. This is unbalanced (I am referring to individual chromosomes). Together, we still have 200% genetic material but individuall it is not 100%.
Chapter 6 Solutions
Genetics: Analysis and Principles
Ch. 6.1 - 1. Genetic linkage occurs because
a. genes that...Ch. 6.1 - In the experiment by Bateson and Punnett, which of...Ch. 6.2 - Prob. 1COMQCh. 6.2 - Prob. 2COMQCh. 6.2 - 3. For a chi square analysis involving genes that...Ch. 6.3 - Answer the multiple-choice questions based on the...Ch. 6.3 - Answer the multiple-choice questions based on the...Ch. 6.4 - 1. A tetrad of spores in an ascus is the product...Ch. 6.4 - Prob. 2COMQCh. 6.5 - 1. The process of mitotic recombination involves...
Ch. 6 - 1. What is the difference in meaning between the...Ch. 6 - 2. When a chi square analysis is applied to solve...Ch. 6 - 3. What is mitotic recombination? A heterozygous...Ch. 6 - 4. Mitotic recombination can occasionally produce...Ch. 6 - 5. A crossover has occurred in the bivalent shown...Ch. 6 - A crossover has occurred in the bivalent shown...Ch. 6 - A diploid organism has a total of 14 chromosomes...Ch. 6 - If you try to throw a basketball into a basket,...Ch. 6 - 9. By conducting testcrosses, researchers have...Ch. 6 - In humans, a rare dominant disorder known as...Ch. 6 - 11. When true-breeding mice with brown fur and...Ch. 6 - Though we often think of genes in terms of the...Ch. 6 - 13. If the likelihood of a single crossover in a...Ch. 6 - 14. In most two-factor crosses involving linked...Ch. 6 - Researchers have discovered that some regions of...Ch. 6 - 16. Describe the unique features of ascomycetes...Ch. 6 - Figure 6.1 shows the first experimental results...Ch. 6 - In the experiment of Figure 6.6, Stern followed...Ch. 6 - 3. Explain the rationale behind a testcross. Is it...Ch. 6 - 4. In your own words, explain why a testcross...Ch. 6 - Explain why the percentage of recombinant...Ch. 6 - 6. If two genes are more thanapart, how would you...Ch. 6 - 7. In Morgan’s three-factor crosses of Figure 6.3,...Ch. 6 - Two genes are located on the same chromosome and...Ch. 6 - 9. Two genes, designated A and B, are locatedfrom...Ch. 6 - 10. Two genes in tomatoes areapart; normal fruit...Ch. 6 - In the tomato, three genes are linked on the same...Ch. 6 - A trait in garden peas involves the curling of...Ch. 6 - Prob. 13EQCh. 6 - 14. In the garden pea, several different genes...Ch. 6 - A sex-influenced trait is dominant in males and...Ch. 6 - Three recessive traits in garden pea plants are as...Ch. 6 - In mice, a trait called snubnose is recessive to a...Ch. 6 - 18. In Drosophila, an allele causing vestigial...Ch. 6 - 19. Three autosomal genes are linked along the...Ch. 6 - 20. Let’s suppose that two different X-linked...Ch. 6 - Prob. 21EQCh. 6 - In mice, a dominant allele that causes a short...Ch. 6 - 2. In Chapter 3, we discussed the idea that the X...Ch. 6 - Mendel studied seven traits in pea plants, and the...
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- In humans, chromosome 16 sometimes has a heavily stained area near the centromere. This feature can be seen in a microscope, but otherwise has no effect on the phenotype of the person carrying it. When such a “blob" exists on a given copy of chromosome 16, it is a constant feature of that chromosome and is inherited. A couple conceived a child, but the fetus had multiple abnormalities and was miscarried. e.g., The fetus had three copies of chromosome 16, where 2 of the 3 copies of chromosome 16 had large blobs. Both of the mother's copies of chromosome 16 lacked blobs, but the father was heterozygous for blobs. The fetus was formed from a fertilization event that included a gamete produced by the in which nondisjunction occurred during the meiotic division. Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a mother; first. mother; second. father; first. C Your answer d father; second. E3 Fullso L e Insufficient information is provided…arrow_forwardTwo phenotypically normal parents produce a phenotypically abnormal child in which chromosome 5 is missing part of its long arm but has a piece of chromosome 7 attached to it. The child also has one normal copy of chromosome 5 and two normal copies of chromosome 7. With regard to chromosomes 5 and 7, what do you think are the chromosomal compositions of the parents? Would it most likely be reciprocal translocation? It wouldn't be simple translocation because then the child would have the entirety of one chromosome and only some of the other, but in this case, there is only partial chromosome 5 and chromosome 7?arrow_forwardA cytogeneticist has collected tissue samples from members of a certain butterfly species. Some of the butterflies were located in Canada, and others were found in Mexico. Through karyotyping, the cytogeneticist discovered that chromosome 5 of the Canadian butterflies has a large inversion compared with chromosome 5 of the Mexican butterflies. The Canadian butterflies were inversion homozygotes, whereas the Mexican butterflies had two normal copies of chromosome 5. 1) Would a cross between Mexican and Canadian butterflies produce phenotypically normal offspring? and 2) Would the offspring of the cross (so F2 generation) be fertile?arrow_forward
- The karyotype of a young girl who is affected with Down syndrome revealed that she has 46 chromosomes. Her phenotypically normal older brother's karyotype revealed that he has 45 chromosomes. (a) Propose an explanantion for the chromosome number in both children (b) What would you expect the chromosome number of the parents of these two children?arrow_forwardIn humans, chromosome 16 sometimes has a heavily stained area in the long arm near the centromere. This feature can be seen through the microscope but has no effect on the phenotype of the person carrying it. When such a “blob” exists on a particular copy of chromosome 16, it is a constant feature of that chromosome and is inherited. A couple conceived a child, but the fetus had multiple abnormalities and was miscarried. When the chromosomes of the fetus were studied, it was discovered that it had three copies of chromosome 16 (it was trisomic for chromosome 16), and that two of the three chromosome 16s had large blobs. Both chromosome 16 homologs in the mother lacked blobs, but the father was heterozygous for blobs. Which parent experienced nondisjunction, and in which meiotic division did it occur?arrow_forwardIn corn, the genes v (virescent seedlings), pr (red aleurone), and bm (brown midrib) are all on chromosome 5, but not necessarily in the order given. The cross: v+ pr bm/ v pr+ bm+ with v pr bm/ v pr bm produces 1000 progeny with the following phenotypes: v+ pr bm 226 v pr+ bm+ 229 v+ pr bm+ 153 v pr+ bm 185 v+ pr+ bm 59 v pr bm+ 71 v+ pr+ bm+ 36 v pr bm 41 What is the gene order, and the (b) genetic map of these three genes?arrow_forward
- In a human genetic study, a family with five phenotypicallynormal children was investigated. Two children were “homozygous”for a Robertsonian translocation between chromosomes19 and 20 (they contained two identical copies of the fusedchromosome). They have only 44 chromosomes but a completegenetic complement. Three of the children were “heterozygous”for the translocation and contained 45 chromosomes,with one translocated chromosome plus a normal copy of bothchromosomes 19 and 20. Two other pregnancies resulted instillbirths. It was later discovered that the parents were firstcousins. Based on this information, determine the chromosomecompositions of the parents. What led to the stillbirths? Whywas the discovery that the parents were first cousins a key pieceof information in understanding the genetics of this family?arrow_forwardThe genes that codes for the creation of certain blood groups are located on chromosome "XGp22.3", chromosome "12p12.3", chromosome "2q14.3", and so on. What is this chromosome terminology? What does it mean?arrow_forwardA cytogeneticist has collected tissue samples from members of acertain butterfly species. Some of the butterflies were located inCanada, and others were found in Mexico. Through karyotyping,the cytogeneticist discovered that chromosome 5 of the Canadianbutterflies had a large inversion compared with chromosome 5 ofthe Mexican butterflies. The Canadian butterflies were inversionhomozygotes, whereas the Mexican butterflies had two normalcopies of chromosome 5.Explain whether a mating between Canadian and Mexicanbutterflies would produce phenotypically normal offspring?arrow_forward
- Mitotic recombination can occasionally produce a twin spot.Let’s suppose an animal species is heterozygous for two genesthat govern fur color and length: one gene affects pigmentation,with dark pigmentation (A) dominant to albino (a); the other geneaffects hair length, with long hair (L) dominant to short hair (l).The two genes are linked on the same chromosome. Let’s assume ananimal of this species is AaLl; A is linked to l, and a is linked to L.Draw the chromosomes labeled with these alleles, and explainhow mitotic recombination could produce a twin spot with onespot having albino pigmentation and long fur and the other havingdark pigmentation and short fur.arrow_forwardPeople with Down syndrome have an extra copy of chromosome 21, for a total of 47 chromosomes. However, in a few cases of Down syndrome, 46 chromosomes are present. This total includes two normal-looking chromosomes 21, one normal chromosome 14, and a longer-than-normal chromosome 14. Interpret this observation. How can these individuals have 46 chromosomes?arrow_forwardIn a germline progenitor cell before DNA replication (2N), a translocation occurred between a telocentric and submetacentric chromosome resulting in a translocation heterozygote. The location of the translocation is illustrated below. Draw the Prophase I pairing conformation that would result from this translocation. The four types of chromosomes you have now can be labeled as follows: T-WT (telocentric wild type), T-TL (telocentric translocation), SM-WT (submetacentric wild type), and SM-TL (submetacentric translocation). Using these labels, list (please do not draw) the possible outcomes of Anaphase I and the possible phenotypes for each outcome. Please explain your reasoning for each phenotype in a few words. asaparrow_forward
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