Microbiology Fundamentals: A Clinical Approach
3rd Edition
ISBN: 9781259709227
Author: Marjorie Kelly Cowan Professor, Heidi Smith
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 5.3, Problem 10AYP
Discuss both persistent and transforming infections.
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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.
b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake?
Options:
A. Dose; Increase dose
B. Dose; Decrease dose
C. Dose; Do not change dose
D. Interval; Increase the interval between doses (give the drug less frequently)
E. Interval; Decrease the interval between doses (give the drug more frequently)
F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
Chapter 5 Solutions
Microbiology Fundamentals: A Clinical Approach
Ch. 5.1 - Explain what it means when viruses are described...Ch. 5.1 - Identify better terms for viruses than alive or...Ch. 5.1 - Which statements are accurate regarding properties...Ch. 5.2 - Prob. 3AYPCh. 5.2 - Describe the function and structure(s) of viral...Ch. 5.2 - Distinguish between enveloped and naked viruses.Ch. 5.2 - Prob. 6AYPCh. 5.2 - Diagram the possible nucleic acid configurations...Ch. 5.2 - Medical Moment Q. Antibiotics targeting bacteria...Ch. 5.3 - Diagram the five-step life cycle of animal...
Ch. 5.3 - Define the term cytopathic effect and provide one...Ch. 5.3 - Discuss both persistent and transforming...Ch. 5.3 - Provide thorough descriptions of both lysogenic...Ch. 5.3 - Prob. 2NPCh. 5.3 - Prob. 3NPCh. 5.4 - List the three principal purposes of cultivating...Ch. 5.4 - Describe three ways in which viruses are...Ch. 5.4 - Prob. 4NPCh. 5.5 - Prob. 14AYPCh. 5.5 - Prob. 2MMCh. 5.5 - Prob. 5NPCh. 5.6 - Analyze the relative importance of viruses in...Ch. 5.6 - Discuss the primary reason that antiviral drugs...Ch. 5 - ___% of human DNA is thought to consist of viral...Ch. 5 - Prob. 2QCh. 5 - Construct a scenario in which viral latency and...Ch. 5 - Prob. 4QCh. 5 - If viruses that normally form envelopes were...Ch. 5 - Viruses use the host cell cytoplasmic space as...Ch. 5 - The general steps in a viral multiplication cycle...Ch. 5 - Compare and contrast the processes of latency and...Ch. 5 - Pathogenic bacteria lysogenized by phages can...Ch. 5 - When phage nucleic acid is incorporated into the...Ch. 5 - Prob. 11QCh. 5 - Prob. 12QCh. 5 - Prob. 13QCh. 5 - Prob. 14QCh. 5 - Prob. 15QCh. 5 - Prob. 16QCh. 5 - Prob. 17QCh. 5 - Construct an argument for whether humans or...Ch. 5 - Since 2000, the number of orders of viruses...Ch. 5 - Prob. 20QCh. 5 - Prob. 21QCh. 5 - Prob. 1VC
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