BROOKER BIOLOGY
5th Edition
ISBN: 9781307656152
Author: BROOKER
Publisher: MCG/CREATE
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Chapter 50.5, Problem 2CC
Summary Introduction
To predict: The part of the cell having the receptor for the steroid hormone 20-hydroxyecdysone.
Introduction: During the process of larval growth and metamorphosis in insects, neurosecretory cells present in the brain secrete a hormone called prothoracicotropic hormone. This hormone stimulates prothoracic glands which in turn secrete a steroid hormone called 20-hydroxyecdysone in the hemolymph.
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Where in the cell would you expect to find an activated, ligand-bound steroid hormone receptor?
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Chapter 50 Solutions
BROOKER BIOLOGY
Ch. 50.2 - Prob. 1CSCh. 50.3 - Prob. 1CSCh. 50.3 - Prob. 1EQCh. 50.3 - Prob. 2EQCh. 50.3 - Prob. 3EQCh. 50.4 - Prob. 1CCCh. 50.4 - Prob. 1CSCh. 50.4 - Prob. 2CCCh. 50.5 - Prob. 1CCCh. 50.5 - Prob. 2CC
Ch. 50 - Which is the defining feature of hormones? a. They...Ch. 50 - Steroid hormones are synthesized from ______blank...Ch. 50 - Prob. 3TYCh. 50 - Prob. 4TYCh. 50 - Prob. 5TYCh. 50 - Prob. 6TYCh. 50 - Which of the following pairs of hormones are...Ch. 50 - In invertebrates, molting of larvae is stimulated...Ch. 50 - Which of the following is true of the adrenal...Ch. 50 - Prob. 10TYCh. 50 - Prob. 1CQCh. 50 - Distinguish between type 1 and type 2 diabetes...Ch. 50 - Core Concept: Systems Organ systems often exert...Ch. 50 - Discuss the roles of hormones in growth and...Ch. 50 - Prob. 2COQ
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- Which of the following hormone describes the signal transduction mechanisms for estrogen a steroid hormone ?arrow_forwardWhat characteristics of a hormone receptor make itspecific for one type of hormone?arrow_forwardExplain why polar hormones cannot regulate their target cells without using second messengers. Alsoexplain in a step-by-step manner how cyclic AMP is used as a second messenger in hormone action.arrow_forward
- What cellular response (up-regulation or down-regulation) would you predict occurs in response to high doses of a drug that binds to a specific hormone receptor? Will more or less of the drug be required for the same response over time? Explain.arrow_forwardSuppose that the circulating concentration of hor-mone is 10–10 M and the Kd for binding to its receptor is 10–8M. What fraction of the receptors will have hormone bound?If a meaningful physiological response occurs when 50% ofthe receptors have bound a hormone molecule, how muchwill the concentration of hormone have to rise to elicit aresponse? The fraction of receptors (R) bound to hormone(H) to form a receptor–hormone complex (R–H) is [R–H]/([R] + [R–H]) = [R–H]/[R]TOT = [H]/([H] + Kd).arrow_forwardOverexpression of this receptor in the cells of the adrenal gland causes Cushing's syndrome, a disease caused by the overproduction of cortisol. One strategy that scientists have employed to treat this disease is the use of small molecules that bind to, but do not activate, MC2R. This type of molecule is generically referred to as an antagonist. How can an antagonist bind to the same receptor as ACTH but not activate it? O a. The antagonist can bind covalently while ACTH binds non-covalently O b. The antagonist is only partially complimentary to the binding pocket of MC2R O The antagonist binds to ACTH and blocks it from binding to the receptor properly O d. The antagonist is the exact same structure as ACTH but since it is synthetic it doesn't work One cause of Cushing's syndrome is the inappropriate production of GPCRS in the adrenal gland that are not normally present in those cells. When these receptors are activated they result in the production of cortisol. Which statement about…arrow_forward
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- How would the presence of a molecule that blocks adenylate cyclase affect the activity of a hormone that produces cellular effects through cAMP?arrow_forwardWhat general features make a chemical compound a hormone, and how do hormones achieve specificity for certain kinds of target cell?arrow_forwardWhat is an example of a protein hormone?arrow_forward
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