WHAT IS LIFE? A GUIDE TO BIO 3E+LAUNCHPA
WHAT IS LIFE? A GUIDE TO BIO 3E+LAUNCHPA
3rd Edition
ISBN: 9781319103316
Author: PHELAN
Publisher: Macmillan Higher Education
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Chapter 5, Problem 9MC
Summary Introduction

Introduction:

Mutations can be of three types – additions, deletions and substitution.

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The figure shows the position of two of these mutations a and b. The nucleotides are altered in these 2 different swo-1 mutant alleles. Use the genetic table to describe any AA changes.Name the type of mutation and describe its effect on swo-1 mRNA and protein for each of the mutations. 3. The swo-1 a mutation (insertion between C and G). 4. The swo-1 b mutation (C-to-T mutation for indicated C). 5. The swo-1 a mutation leads to worms with more body wall muscle, whereas worms with the swo-1 b mutation are not able to move. Based on these phenotypes and the findings from questions 3 and 4, describe the role thewild-type version of this protein plays in muscle function.
How would each of the following types of mutations affect proteinfunction or the amount of functional protein that is expressed froma gene?A. Nonsense mutationB. Missense mutationC. Up promoter mutationD. Mutation that affects splicing
Which type of mutation would expect would have no effect on a protein coding gene in eukaryotes?       a.a single base substitution that creates a splice site mutation       b.a single base substitution that creates a synonymous mutation       c.a single base deletion that creates a frameshift near the 3' end of the open reading frame       d.a single base substitution that creates a non-conservative missense mutation       e.a single base substitution that creates a conservative missense mutation
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY