Microbiology: An Introduction
Microbiology: An Introduction
12th Edition
ISBN: 9780321929150
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: PEARSON
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Chapter 5, Problem 2CAE

The drug Hivid, also called ddC, inhibits DNA synthesis. It is used to treat HIV infection and AIDS. Compare the following illustration of ddC to the structure of DNA nucleotides In Figure 2.16 on page 44. How does this drug work?

Chapter 5, Problem 2CAE, The drug Hivid, also called ddC, inhibits DNA synthesis. It is used to treat HIV infection and AIDS.

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Which of the following nucleotides found in DNA is dGTP? Note, hydrogens bound to carbon atoms are not shown.
Which of the following is correct regarding nucleotide structure?   Removal of the ribose-phosphate groups from thymidylic acid or thymidylate yields thymidine   Removal of the ribose-phosphate groups from cytidine yields cytosine   Removal of the phosphate group from guanylic acid or guanylate yields guanine.   Removal of the phosphate group from adenylate or adenylic acid yields adenosine
DNA in the form of a double helix must be associated with cations, usually Mg²+ . Why is this requirement the case?

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Microbiology: An Introduction

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