The two chirality centres in chloramphenicol are to be identified and a three-dimensional formula for chloramphenicol is to be written. Concept introduction: The molecules or compounds which are non-superimposable or not identical with its mirror image are known as chiral molecules. The pair of two mirror images which are non-identical are known as enantiomers and these are optically active. The objects or molecules which are superimposable with their mirror images are achiral objects or molecules and these objects have a centre of symmetry or plane of symmetry. The achiral compounds in which plane of symmetry is present internally and consists of chiral centres are known as meso compounds but they are optically inactive. The stereoisomers which are non-superimposable on each other and not mirror images of each other are known as diastereomers. Chiral molecules are capable of rotating plane polarized light The molecules which are superimposable or identical with their mirror images are known as achiral molecules, and achiral molecules are not capable of rotating the plane-polarised light. Plane of symmetry is the plane that bisects the molecule in two equal halves, such that they are mirror images of each other. Compounds having plane of symmetry are usually achiral as they do not have different atoms around the central carbon atom. The enantiomers, in which the path traced from the highest atomic number to the lowest atomic number is in an anticlockwise direction, are designated as S . The enantiomers, in which the path traced from the highest atomic number to the lowest atomic number is in the clockwise direction, are designated as R . The compounds or molecules which are superimposable with its mirror images are achiral objects or molecules and these objects have a centre of symmetry or plane of symmetry.

Question

Want to see the full answer?

Answer 1

Question

Chapter 5, Problem 25PP

Interpretation Introduction

Interpretation:

The two chirality centres in chloramphenicol are to be identified and a three-dimensional formula for chloramphenicol is to be written.

Concept introduction:

The molecules or compounds which are non-superimposable or not identical with its mirror image are known as chiral molecules.

The pair of two mirror images which are non-identical are known as enantiomers and these are optically active.

The objects or molecules which are superimposable with their mirror images are achiral objects or molecules and these objects have a centre of symmetry or plane of symmetry.

The achiral compounds in which plane of symmetry is present internally and consists of chiral centres are known as meso compounds but they are optically inactive.

The stereoisomers which are non-superimposable on each other and not mirror images of each other are known as diastereomers.

Chiral molecules are capable of rotating plane polarized light

The molecules which are superimposable or identical with their mirror images are known as achiral molecules, and achiral molecules are not capable of rotating the plane-polarised light.

Plane of symmetry is the plane that bisects the molecule in two equal halves, such that they are mirror images of each other.

Compounds having plane of symmetry are usually achiral as they do not have different atoms around the central carbon atom.

The enantiomers, in which the path traced from the highest atomic number to the lowest atomic number is in an anticlockwise direction, are designated as S.

The enantiomers, in which the path traced from the highest atomic number to the lowest atomic number is in the clockwise direction, are designated as R.

The compounds or molecules which are superimposable with its mirror images are achiral objects or molecules and these objects have a centre of symmetry or plane of symmetry.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

3. Assign absolute configuration (Rors) to each chirality center. a. H Nitz C. он b. 0 H-C. C H 7 C. ་-4 917-417 refs H 1つ ८ ડુ d. Но f. -2- 01 Ho -OH 2HN

How many signals do you expect in the H NMR spectrum for this molecule? Br Br Write the answer below. Also, in each of the drawing areas below is a copy of the molecule, with Hs shown. In each copy, one of the H atoms is colored red. Highlight in red all other H atoms that would contribute to the same signal as the H already highlighted red. Note for advanced students: In this question, any multiplet is counted as one signal. Number of signals in the 'H NMR spectrum. For the molecule in the top drawing area, highlight in red any other H atoms that will contribute to the same signal as the H atom already highlighted red. If no other H atoms will contribute, check the box at right. No additional Hs to color in top molecule For the molecule in the bottom drawing area, highlight in red any other H atoms that will contribute to the same signal as the H atom already highlighted red. If no other H atoms will contribute, check the box at right. No additional Hs to color in bottom molecule

In the drawing area below, draw the major products of this organic reaction: 1. NaOH ? 2. CH3Br If there are no major products, because nothing much will happen to the reactant under these reaction conditions, check the box under the drawing area instead. No reaction. Click and drag to start drawing a structure. ☐ : A ค