Muscle and bone strength are attained by the production of vitamin D 3 . Vitamin D 3 is very essential for strong bones and the lack of it can cause reduction in bone density. It helps in absorption of calcium to the bones.

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Chapter 5, Problem 14RQ

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Muscle and bone strength are attained by the production of vitamin D₃. Vitamin D₃ is very essential for strong bones and the lack of it can cause reduction in bone density. It helps in absorption of calcium to the bones.

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Kinetics: One-Compartment First-Order Absorption 1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration. Using this data and set of graphs, determine:(calculate for each variable) (a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e)absolute ip bioavailability, Fip (f) absolute po bioavailability, Fpo

3. A promising new drug is being evaluated in human trials. Based on preliminary human tests, this drug is most effective when plasma levels exceed 30 mg/L. Measurements from preliminary tests indicate the following human pharmacokinetic parameter values: t1/2,elim = 4.6hr, t1/2,abs = 0.34hr, VD = 0.29 L/kg, Foral = 72%. Based on these parameters, estimate the following if a 49 kg woman were to receive a 1000mg oral dose of this drug: (a) Estimate the plasma concentration of the drug at 1hr, 6 hr, and 20hr after taking the drug ( Concentration estimate) (b) Estimate the time for maximum plasma concentration (tmax). (c) Estimate the maximum plasma concentration (Cmax). (d) Estimate the time at which the plasma level first rises above 30 mg/L. (Note this is a trial and error problem where you must guess a time, plug it into the concentration equation, and determine if it is close to 30 mg/L. Hint: based on part (a) it should be apparent that the answer is less than 1hr.) (e)…

List substitutions in your diet you could make to improve it based on what you know now about a balanced diet. For instance, if you like to drink soda, you might substitute skim milk or water for some of the soft drinks you consumed. List the item you wish to replace with the new item and what you hope to accomplish with that substitution. Be sure to choose foods you know that you'd enjoy and you consider more "healthful." If you feel your diet is already balanced, describe how you accomplish your balanced intake and when you began eating this way.

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Question

Chapter 5, Problem 14RQ

Summary Introduction

Introduction:

Muscle and bone strength are attained by the production of vitamin D₃. Vitamin D₃ is very essential for strong bones and the lack of it can cause reduction in bone density. It helps in absorption of calcium to the bones.

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Answer 3

Question

Chapter 5, Problem 14RQ

Summary Introduction

Introduction:

Muscle and bone strength are attained by the production of vitamin D₃. Vitamin D₃ is very essential for strong bones and the lack of it can cause reduction in bone density. It helps in absorption of calcium to the bones.

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Answer 4

Question

Chapter 5, Problem 14RQ

Summary Introduction

Introduction:

Muscle and bone strength are attained by the production of vitamin D₃. Vitamin D₃ is very essential for strong bones and the lack of it can cause reduction in bone density. It helps in absorption of calcium to the bones.

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Answer 5

Chapter 5, Problem 14RQ

Summary Introduction

Introduction:

Muscle and bone strength are attained by the production of vitamin D₃. Vitamin D₃ is very essential for strong bones and the lack of it can cause reduction in bone density. It helps in absorption of calcium to the bones.

Answer 6

Chapter 5, Problem 14RQ

Summary Introduction

Introduction:

Muscle and bone strength are attained by the production of vitamin D₃. Vitamin D₃ is very essential for strong bones and the lack of it can cause reduction in bone density. It helps in absorption of calcium to the bones.

Answer 7

Chapter 5, Problem 14RQ

Summary Introduction

Introduction:

Muscle and bone strength are attained by the production of vitamin D₃. Vitamin D₃ is very essential for strong bones and the lack of it can cause reduction in bone density. It helps in absorption of calcium to the bones.

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Ch. 5 - Identity the layers of the epidermis.Ch. 5 - Dandruff is caused by excessive shedding of cells...Ch. 5 - A splinter that penetrates to the third layer of...Ch. 5 - Why does taking a bath cause wrinkly fingertips...Ch. 5 - Some criminals sand the Lips of their fingers so...Ch. 5 - Prob. 6CP Ch. 5 - Prob. 7CP Ch. 5 - Prob. 8CP Ch. 5 - Prob. 9CP Ch. 5 - Prob. 10CP

Muscle and bone strength are attained by the production of vitamin D 3 . Vitamin D 3 is very essential for strong bones and the lack of it can cause reduction in bone density. It helps in absorption of calcium to the bones.

Solution Summary: The author explains that muscle and bone strength are attained by the production of vitamin D 3, which helps in absorption of calcium to the bones.

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Introduction:

Muscle and bone strength are attained by the production of vitamin D₃. Vitamin D₃ is very essential for strong bones and the lack of it can cause reduction in bone density. It helps in absorption of calcium to the bones.

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Chapter 5 Solutions

Muscle and bone strength are attained by the production of vitamin D 3 . Vitamin D 3 is very essential for strong bones and the lack of it can cause reduction in bone density. It helps in absorption of calcium to the bones.

Solution Summary: The author explains that muscle and bone strength are attained by the production of vitamin D 3, which helps in absorption of calcium to the bones.

Videos

Introduction: Muscle and bone strength are attained by the production of vitamin D3. Vitamin D3 is very essential for strong bones and the lack of it can cause reduction in bone density. It helps in absorption of calcium to the bones.

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Chapter 5 Solutions

Introduction:

Muscle and bone strength are attained by the production of vitamin D₃. Vitamin D₃ is very essential for strong bones and the lack of it can cause reduction in bone density. It helps in absorption of calcium to the bones.