Campbell Biology, Books a la Carte Plus Mastering Biology with eText -- Access Card Package (10th Edition)
10th Edition
ISBN: 9780133922851
Author: Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Publisher: PEARSON
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Chapter 5, Problem 11TYU
SCIENTIFIC INQUIRY Suppose you are a research assistant in a lab studying DNA-binding proteins. You have been given the amino acid sequences of all the proteins encoded by the genome of a certain species and have been asked to find candidate proteins that could bind DNA. What type of amino acids would you expect to see in the DNA-binding regions of such proteins? Explain your thinking.
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Suppose that the gene for a protein 500 amino acids in length undergoes a mutation. If the mutation causes the synthesis of a
mutant protein in which just one of the 500 amino acids is incorrect, the protein may lose its biological function.
How can a small change in a protein's sequence inactivate the protein?
The catalytic site of the protein may be malformed, preventing complementary fit.
RNA may not recognize the altered DNA sequence, and bases may pair incorrectly.
It may alter the shape of the protein's molecular chaperone, preventing proper protein folding.
The active site may base pair incorrectly with the complementary DNA strand.
The resulting protein may fold incorrectly and may not attain its native conformation.
Suppose you are provided with a sequence of nucleotides. How would you determine if the sequence is of mRNA, tRNA, or DNA molecules?
Give typing answer with explanation and conclusion to all parts
Total nucleic acids are extracted from a culture of cells and are then mixed with resin beads to which the polynucleotide 5'-TITTTITTTTTTTTTTTTTTTT-3' has been covalently attached. After a short incubation, the beads are then extracted from the mixture. When you analyze the cellular nucleic acids that have stuck to the beads, which of the following molecules do you expect to be most abundant?
Chapter 5 Solutions
Campbell Biology, Books a la Carte Plus Mastering Biology with eText -- Access Card Package (10th Edition)
Ch. 5.1 - What are the four main classes of large biological...Ch. 5.1 - How many molecules of water are needed to...Ch. 5.1 - WHAT IF? If you eat a piece of fish, what...Ch. 5.2 - Write the formula for a monosaccharide that has...Ch. 5.2 - Prob. 2CCCh. 5.2 - WHAT IF? After a cow is given antibiotics to...Ch. 5.3 - Compare the structure of a fat (triglyceride) with...Ch. 5.3 - Why are human sex hormones considered lipids?Ch. 5.3 - Prob. 3CCCh. 5.4 - What parts of a polypeptide participate in the...
Ch. 5.4 - Prob. 2CCCh. 5.4 - WHAT IF? Where would you expect a polypeptide...Ch. 5.5 - Prob. 1CCCh. 5.5 - DRAW IT In a DNA double helix, a region along one...Ch. 5.6 - How would sequencing the entire genome of an...Ch. 5.6 - Given the function of DNA, why would you expect...Ch. 5 - What is the fundamental basis for the differences...Ch. 5 - Compare the composition, structure, and function...Ch. 5 - Why are lipids not considered to be polymers or...Ch. 5 - Explain the basis for the great diversity of...Ch. 5 - What role does complementary base pairing play in...Ch. 5 - Prob. 5.6CRCh. 5 - Prob. 1TYUCh. 5 - The enzyme amylase can break glycosidic linkages...Ch. 5 - Prob. 3TYUCh. 5 - The structural level of a protein least affected...Ch. 5 - Enzymes that break down DNA catalyze the...Ch. 5 - The molecular formula for glucose is C6H12O6. What...Ch. 5 - Which of the following pairs of base sequences...Ch. 5 - Construct a table that organizes the following...Ch. 5 - Prob. 9TYUCh. 5 - EVOLUTION CONNECTION Comparisons of amino acid...Ch. 5 - SCIENTIFIC INQUIRY Suppose you are a research...Ch. 5 - WRITE ABOUT A THEME: ORGANIZATION Proteins, which...Ch. 5 - SYNTHESIZE YOUR KNOWLEDGE Given that the function...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Determine the effect of the following mutations on the DNA sequence. In each case, the mutation is described after the sequence. Guanine nucleotide (G shown in red in the DNA sequence below) was substituted by C Write out the sequence of the mutated DNA and the protein made from it. What is the effect of this mutation on the protein? (For example, how will the mutation affect the length and sequence of the protein? What about the function of the protein?)arrow_forwardDetermine the effect of the following mutations on the DNA sequence. In each case, the mutation is described after the sequence. Guanine nucleotide (G shown in red in the DNA sequence below) was substituted by C Write out the sequence of the mutated DNA and the protein made from it. What is the effect of this mutation on the protein? (For example, how will the mutation affect the length and sequence of the protein? What about the function of the protein?) 3' TACATGGTTGTGCTAATT 5' Carrow_forwardGiven the following DNA strand: TACAGAGATAACCGAATT A. Write the corresponding strand that would form the other half of the DNA molecule. B. Transcribe the original DNA strand (TACAGAGATAACCGAATT) and write the sequence of bases found in the resulting messenger RNA molecule. C. Translate your messenger RNA molecule and write the sequence of amino acids in the resulting protein (the genetic code is provided below).arrow_forward
- Suppose you are studying two different mutations in a gene that codes for a protein. In the first, a nonsense mutation occurs near the beginning of the gene. In the second, a nonsense mutation occurs near the end of a gene. Which mutation is more likely to affect the proteins function? Why?arrow_forwardStudents are modeling MRNA during the process of protein synthesis. Which answer choice correctly describes the model of the MRNA strand being transcribed? The MRNA strand is complimentary to the DNA template strand; however, uracil instead of adenine is paired with thymine. O The MRNA strand is complimentary to the DNA template strand; however, uracil instead of thymine is paired with adenine. O The MRNA strand is an exact copy the DNA template strand; however, uracil instead of adenine is paired with thymine. The MRNA strand is an exact copy the DNA template strand; however, uracil instead of thymine is paired with adenine. a |理 2 Type here to searcharrow_forwardBoring magasanik collected data on the proportion of each base in RNA from different species. To compare the relative amount of each base, he standardized thr value of adenine to 10. Relative amounts of other bases were calculated based on this value for adenine. For each of the listed body parts listed, give the proportion of purine to pyrimidines in a decimal form. Rat liver nuclei Rabbit liver nuclei Cat brainarrow_forward
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