Biology (MindTap Course List)
11th Edition
ISBN: 9781337392938
Author: Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher: Cengage Learning
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Chapter 45, Problem 5TYU
Summary Introduction
Introduction: Cancer is caused due to abnormal cell cycle control system. It undergoes several genetic and epigenetic alterations that cause uncontrolled proliferation of cells. The cell undergoes an oncogenic transformation in several hits. Cancer cell makes own growth factors. Therefore, they do not depend on the supply of external growth factors. Cancer cells express specific cell surface antigen that helps in evading the immune destruction.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 45 Solutions
Biology (MindTap Course List)
Ch. 45.1 - Prob. 1LOCh. 45.1 - Compare, in general terms, the immune responses...Ch. 45.1 - Prob. 1CCh. 45.1 - In general, how are vertebrate immune responses...Ch. 45.2 - Describe innate immune responses, including...Ch. 45.2 - Prob. 1CCh. 45.2 - Prob. 2CCh. 45.2 - Prob. 3CCh. 45.2 - VISUALIZE Draw a diagram illustrating the main...Ch. 45.3 - Prob. 4LO
Ch. 45.3 - Prob. 5LOCh. 45.3 - How are cell-mediated immunity and...Ch. 45.3 - Prob. 2CCh. 45.3 - Prob. 3CCh. 45.4 - Describe the sequence of events in cell-mediated...Ch. 45.4 - Prob. 1CCh. 45.5 - Summarize the sequence of events in...Ch. 45.5 - Prob. 8LOCh. 45.5 - Prob. 9LOCh. 45.5 - Prob. 10LOCh. 45.5 - Prob. 1CCh. 45.5 - Prob. 2CCh. 45.5 - Prob. 3CCh. 45.5 - Prob. 4CCh. 45.6 - Prob. 11LOCh. 45.6 - Describe examples of hypersensitivity, including...Ch. 45.6 - Prob. 1CCh. 45.6 - Prob. 2CCh. 45.6 - Prob. 3CCh. 45.6 - Prob. 4CCh. 45.6 - What is the immunological basis for graft...Ch. 45 - Innate immune responses include all but (a)...Ch. 45 - Cytokines (a) are regulatory Toll-like receptors...Ch. 45 - Which of the following is not an action of...Ch. 45 - Prob. 4TYUCh. 45 - Prob. 5TYUCh. 45 - Prob. 6TYUCh. 45 - Prob. 7TYUCh. 45 - Prob. 8TYUCh. 45 - Prob. 9TYUCh. 45 - Which sequence most accurately describes...Ch. 45 - VISUALIZE Label the following diagram and explain...Ch. 45 - Specificity, diversity, and memory are key...Ch. 45 - Prob. 13TYUCh. 45 - PREDICT A playmate in kindergarten exposes John...Ch. 45 - Prob. 15TYUCh. 45 - Prob. 16TYU
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