To distinguish: Among psychological dependence, tolerance, and drug addiction and describe the biological actions and effects on the mood of alcohol, antidepressants, barbiturates, anti-anxiety drugs, antipsychotic drugs, opiates, stimulants, hallucinogens, and marijuana. Introduction: Drug abuse is slowly increasing and becoming a very common phenomenon amongst teenagers and young adults these days. Most of the commonly abused drugs affect mood by changing the levels of certain hormones such as, dopamine, and serotonin. Alcohol is abused most commonly and has several harmful effects on humans. Many other drugs such as antidepressants, which are prescribed to cure the psychological disorder, are also being abused.

Question

a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved

Answer 1

Question

100%

Chapter 42.6, Problem 12LO

Summary Introduction

To distinguish: Among psychological dependence, tolerance, and drug addiction and describe the biological actions and effects on the mood of alcohol, antidepressants, barbiturates, anti-anxiety drugs, antipsychotic drugs, opiates, stimulants, hallucinogens, and marijuana.

Introduction: Drug abuse is slowly increasing and becoming a very common phenomenon amongst teenagers and young adults these days. Most of the commonly abused drugs affect mood by changing the levels of certain hormones such as, dopamine, and serotonin. Alcohol is abused most commonly and has several harmful effects on humans. Many other drugs such as antidepressants, which are prescribed to cure the psychological disorder, are also being abused.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved

If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose B. Dose; Decrease dose C. Dose; Do not change dose D. Interval; Increase the interval between doses (give the drug less frequently) E. Interval; Decrease the interval between doses (give the drug more frequently) F. Interval; Do not change the interval

What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math