LIFE: THE SCIENCE OF BIOLOGY
LIFE: THE SCIENCE OF BIOLOGY
11th Edition
ISBN: 9781319145125
Author: Sadava
Publisher: MAC HIGHER
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Chapter 41.5, Problem 1R
Summary Introduction

To review:

The working of the cyclosporin drug, which interrupts the development of T cell.

Introduction:

The cyclosporin is a class of immunosuppressant, which is administered to the patients who face organ rejection. The transplanted organ can be rejected by the body due to the cell-mediated immunity, which can be suppressed by the inhibition of the T-cell development. The cyclosporin drug acts by interrupting the development of T cell and suppress the immune system of the patient.

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*Example 2: Tracing the path of an autosomal dominant trait Trait: Neurofibromatosis Forms of the trait: The dominant form is neurofibromatosis, caused by the production of an abnormal form of the protein neurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-cancerous tumors that can interfere with the nervous system and cause blindness. Some tumors can convert to a cancerous form. i The recessive form is a normal protein - in other words, no neurofibromatosis.moovi A typical pedigree for a family that carries neurofibromatosis is shown below. Note that carriers are not indicated with half-colored shapes in this chart. Use the letter "N" to indicate the dominant neurofibromatosis allele, and the letter "n" for the normal allele. Nn nn nn 2 nn Nn A 3 N-
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