LIFE: THE SCIENCE OF BIOLOGY
LIFE: THE SCIENCE OF BIOLOGY
11th Edition
ISBN: 9781319145125
Author: Sadava
Publisher: MAC HIGHER
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Chapter 41, Problem 3Q
Summary Introduction

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The advantage of the gene therapy on the patients who were also given enzyme replacement therapy (ERT).

Introduction:

Immunodeficiency refers to the condition that arises due to the inability of the body’s immune system to efficiently tackle the infectious agents and fight against the diseases. The individual becomes susceptible to even smallest type of infection as the immunity of the body weakens or is totally absent. These diseases can be inherited from one generation to another.

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*Example 2: Tracing the path of an autosomal dominant trait Trait: Neurofibromatosis Forms of the trait: The dominant form is neurofibromatosis, caused by the production of an abnormal form of the protein neurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-cancerous tumors that can interfere with the nervous system and cause blindness. Some tumors can convert to a cancerous form. i The recessive form is a normal protein - in other words, no neurofibromatosis.moovi A typical pedigree for a family that carries neurofibromatosis is shown below. Note that carriers are not indicated with half-colored shapes in this chart. Use the letter "N" to indicate the dominant neurofibromatosis allele, and the letter "n" for the normal allele. Nn nn nn 2 nn Nn A 3 N-
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