Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 4, Problem 6PDQ
List all possible genotypes for the A, B, AB, and O
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For each of the following modes of inheritance, describe the features that will be exhibited in a pedigree in which the trait is present: autosomal recessive, autosomal dominant, X-linked recessive, X-linked dominant, and Y-linked inheritance.
Farmer Brown had two hogs, Olga and Hank. Olga and Hank were normal, healthy hogs, but whenever Farmer Brown crossed them, a few of the piglets had cleft palates. Assuming a simple autosomal basis for cleft palate, what are the genotypes of Olga and Hank, and about what proportion of the piglets are born with a cleft palate?
—Hereditary canine spinal muscular atrophy (HCSMA) is a motor neuron disease in Brittany Spaniels. Breeding studuies within a kindred of more than 125 dogs (Brittany spaniel and beagle-Brittany outcrosses) have established an autosomal dominant inheritance for HCSMA.
Which of the following genotypes would cause the dog to NOT HAVE HCSMA?
Hh
HH
Hh
A and C
B and C–
—(see question above for genotype) is a spaniel who is homozygous recessive for the HCSMA trait had a puppy with a spaniel who was heterozygous for this trait, what is the probability that the puppy would be normal?
0%
25%
50%
75%
100%
Chapter 4 Solutions
Concepts of Genetics (12th Edition)
Ch. 4 - In the guinea pig, one locus involved in the...Ch. 4 - In some plants a red flower pigment, cyanidin, is...Ch. 4 - Below are three pedigrees. For each trait,...Ch. 4 - Researching their family histories, a deaf couple...Ch. 4 - Researching their family histories, a deaf couple...Ch. 4 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 4 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 4 - In shorthorn cattle, coat color may be red, white,...Ch. 4 - In foxes, two alleles of a single gene, P and p,...Ch. 4 - In mice, a short-tailed mutant was discovered....
Ch. 4 - List all possible genotypes for the A, B, AB, and...Ch. 4 - With regard to the ABO blood types in humans,...Ch. 4 - In a disputed parentage case, the child is blood...Ch. 4 - The A and B antigens in humans may be found in...Ch. 4 - In chickens, a condition referred to as creeper...Ch. 4 - In rabbits, a series of multiple alleles controls...Ch. 4 - Three gene pairs located on separate autosomes...Ch. 4 - As in Problem 12, flower color may be red, white,...Ch. 4 - Horses can be cremello (a light cream color),...Ch. 4 - With reference to the eye color phenotypes...Ch. 4 - Pigment in mouse fur is only produced when the C...Ch. 4 - In rats, the following genotypes of two...Ch. 4 - Given the inheritance pattern of coat color in...Ch. 4 - In a species of the cat family, eye color can be...Ch. 4 - In a plant, a tall variety was crossed with a...Ch. 4 - In a unique species of plants, flowers may be...Ch. 4 - Five human matings (15), identified by both...Ch. 4 - A husband and wife have normal vision, although...Ch. 4 - In humans, the ABO blood type is under the control...Ch. 4 - In Drosophila, an X-linked recessive mutation,...Ch. 4 - Another recessive mutation in Drosophila, ebony...Ch. 4 - In Drosophila, the X-linked recessive mutation...Ch. 4 - While vermilion is X-linked in Drosophila and...Ch. 4 - In a cross in Drosophila involving the X-linked...Ch. 4 - Consider the three pedigrees below, all involving...Ch. 4 - In goats, the development of the beard is due to a...Ch. 4 - Predict the F1 and F2 results of crossing a male...Ch. 4 - Two mothers give birth to sons at the same time at...Ch. 4 - Discuss the topic of phenotypic expression and the...Ch. 4 - Prob. 35PDQCh. 4 - Labrador retrievers may be black, brown...Ch. 4 - A true-breeding purple-leafed plant isolated from...Ch. 4 - In Dexter and Kerry cattle, animals may be polled...Ch. 4 - A geneticist from an alien planet that prohibits...Ch. 4 - The following pedigree is characteristic of an...Ch. 4 - Students taking a genetics exam were expected to...Ch. 4 - In four oclock plants, many flower colors are...Ch. 4 - Below is a partial pedigree of hemophilia in the...
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- In addition to the allelic pair determining pattern baldness in man (B,b), consider early baldness to be due to another autosomal allele (E) on a different pair of chromosomes and also dominant in males but recessive in females. The phenotype for ee may be late or nonbaldness depending on sex and the genotype for B, b alleles. Two doubly heterozygous persons marry. What is the phenotype of the male parent? What is the phenotype of the female parent? Give the phenotypic ratio expected among male children of couples such as this one. Show corresponding genotypes for each phenotype mentioned in your phenotypic ratio. Give the phenotypic ratio expected among female children of couples such as this one. Show corresponding genotypes for each phenotype mentioned in your phenotypic ratio.arrow_forwardA light-haired man has blood type O, his wife has dark hair and blood type AB, but her father had light hair. Assume dark hair (H) is dominant to light (h). What is the probability they will have a child with dark hair and blood type A? What is the probability they will have a child with light hair and blood type B? What is the total number of phenotypes their children could show?arrow_forwardThe ABO blood group is one set of blood antigens. There is a separate locus (H) that controls the presentation of these antigens on the cell surface. Individuals who are homozygous, hh, cannot present the antigens of the ABO type (and appear to be O-type). Consider the following cross: P0: IAi Hh x IBi Hh 1. What is this type of inheritance pattern called? Complete a Punnett square to determine are the phenotypic frequencies of the apparent blood groups among the offspring?arrow_forward
- Consider the two very limited unrelated pedigrees shown here. Of the four combinations of X-linked recessive, Xlinked dominant, autosomal recessive, and autosomal dominant, which modes of inheritance can be ruled out in each case? (a) (b) II 1arrow_forwardThalassemia is an inherited anemic disorder in humans. Affected individuals exhibit either a minor anemia or a major anemia. Assuming that only a single gene pair and two alleles are involved in the inheritance of these conditions, is thalassemia a dominant or recessive disorder?arrow_forwardA man with blood type O (genotype ii) has a father with blood type A and a mother with blood type B. Is this man a legitimate child of these parents? What is a possible phenotype of an individual that results from a woman with type AB blood and a man with type B blood? Explain with diagrams.arrow_forward
- (a) Enter the parent phenotypes and complete the Punnett square Inheritance of sex linked recessive tralts Example: Hemophilia Female paront phenotype Inheritance of hemophilia is sex linked. Males with the recessive (hemophilia) allele, are affected. Females can be carriers. (normal female) Xxh (carrier female) ben-N werxhxh (hemophiliac female) leizobXY (normal male) xhy (hemophiliac male) Male parent phenotype: Using the codes: XX eggs (a) Enter the parent phenotypes and complete the Punnett square for a cross between a normal male and a carrier female. sperm (b) Give the ratios for the phenotypes from this cross. Phenotype ratios: Inheritance of sex linked dominant traits Example: Sex linked form of rickets A rare form of rickets is inherited on the X chromosome. Using the codes: XX Female parent phenotype: alvo eo (normal female); XY (normal male) (affected heterozygote female) XRXR (affected female) XRY Male parent phenotype: XRX eggs (affected male) Nor a cross between an…arrow_forwardHypophosphatemia is a dominant genetic disorder caused by a deficiency of phosphates in the blood. Assuming the other parent is free of the disorder, males with the disorder will pass it on to all their daughters, but not their sons. Females with the disorder will pass it on to approximately half of their children. Is this pattern of inheritance autosomal or sex-linked? Draw Punnett squares to show the inheritance pattern of the disorder in each of the two scenarios.arrow_forwardSickle cell anemia is inherited as an autosomal recessive condition. It also exhibits incomplete dominance in that the heterozygous genotype displays a mild form of the disease known as sickle cell trait while individuals with the homozygous recessive genotype have a severe form of SCA. A man who has severe sickle cell anemia marries a woman who suffers from a mild trait. What is the probabilitu they will have a child with severe SCA?What is the probability they will have a child with mild SCA? What is the probability they will have a normal child? Show ALL work using punnett squares.arrow_forward
- Cystic fibrosis is a recessive human condition. A male with Cystic fibrosis and a woman with a dominant phenotype have sevral children, in which one displays Cystic fibrosis. What can you conclude about the genotype of the maternal parent and what is the probability that a child who does not display Cystic fibrosis is heterozygous?arrow_forwardPropose the most likely mode of inheritance (autosomal dominant, autosomal recessive, or X-linked recessive) for the following pedigrees. Affected individuals are shown with filled (black)symbols.arrow_forwardIn humans, being right handed (R) is dominant over being left handed (r), and normal vision (X+) is dominant over color blindness (Xc). Color blindness is a X-linked (a.k.a sex linked) trait. Two right-handed parents with normal vision have a son who is color blind and left handed. What are the genotypes of the parents for right-handedness and color blindness?arrow_forward
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