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Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Textbook Question
Chapter 4, Problem 29PDQ
In a cross in Drosophila involving the X-linked recessive eye mutation white and the autosomally linked recessive eye mutation sepia (resulting in a dark eye), predict the F1 and F2 results of crossing true-breeding parents of the following
- (a) white females × sepia males
- (b) sepia females × white males
Note that white is epistatic to the expression of sepia.
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Students have asked these similar questions
IN DROSOPHILA, AN X-LINKED
RECESSIVE MUTATION, Xm CAUSES
MINIATURE WINGS. LIST
THE F₂ PHENOTYPIC RATIOS IF:
A MINIATURE-WINGED FEMALE IS
CROSSED WITH A NORMAL MALE AND
A MINIATURE-WINGED MALE IS
●
●
CROSSED WITH A NORMAL FEMALE.
WHAT WOULD THE PHENOTYPIC RATIO
FROM (A) BE IF THE MINIATURE-
WINGED GENE WERE AUTOSOMAL?
ASSUME IN ALL CASES THAT THE P1
INDIVIDUALS ARE TRUE-BREEDING.
Consider the following three autosomal recessive mutations in Drosophila:vestigial wings (v); wild type is long (v+)black body color (b); wildtype is gray (b+)plum eyes (p); wildtype is red (p+)A vestigal, gray, red female (homozygous for all three genes) is crossed with a long wing, black, plum male (homozygous for all three genes). The F1 female progeny are mated with triple homozygous recessive males. Here is the phenotypic data for the F2 progeny:vestigal; gray; red 580long wings; black; plum 592vestigal; black; red 45long; gray; plum 40vestigal; black; plum 89long; gray; red 94vestigal; gray; plum 3long; black; red 5A total of 1448 progeny were counted.Which one of the following values is the approximate distance between the plum eye color and black body color loci?
Miniature wings (Xm) in Drosophila result from an X-linked allele that is recessive to
the allele for long wings (X*). Give the genotypes of the parents in the following
cross:
Male parent
Female parent
Male offspring
Female offspring
Long
Miniature
750 miniature
761 long
O male: X* / X* and female X™ /x+
O male: X*/Xt and female Xm /xm
O male: X*/ Y and female Xm /xm
O male: Xm/ Y and female Xm /xm
Chapter 4 Solutions
Concepts of Genetics (12th Edition)
Ch. 4 - In the guinea pig, one locus involved in the...Ch. 4 - In some plants a red flower pigment, cyanidin, is...Ch. 4 - Below are three pedigrees. For each trait,...Ch. 4 - Researching their family histories, a deaf couple...Ch. 4 - Researching their family histories, a deaf couple...Ch. 4 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 4 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 4 - In shorthorn cattle, coat color may be red, white,...Ch. 4 - In foxes, two alleles of a single gene, P and p,...Ch. 4 - In mice, a short-tailed mutant was discovered....
Ch. 4 - List all possible genotypes for the A, B, AB, and...Ch. 4 - With regard to the ABO blood types in humans,...Ch. 4 - In a disputed parentage case, the child is blood...Ch. 4 - The A and B antigens in humans may be found in...Ch. 4 - In chickens, a condition referred to as creeper...Ch. 4 - In rabbits, a series of multiple alleles controls...Ch. 4 - Three gene pairs located on separate autosomes...Ch. 4 - As in Problem 12, flower color may be red, white,...Ch. 4 - Horses can be cremello (a light cream color),...Ch. 4 - With reference to the eye color phenotypes...Ch. 4 - Pigment in mouse fur is only produced when the C...Ch. 4 - In rats, the following genotypes of two...Ch. 4 - Given the inheritance pattern of coat color in...Ch. 4 - In a species of the cat family, eye color can be...Ch. 4 - In a plant, a tall variety was crossed with a...Ch. 4 - In a unique species of plants, flowers may be...Ch. 4 - Five human matings (15), identified by both...Ch. 4 - A husband and wife have normal vision, although...Ch. 4 - In humans, the ABO blood type is under the control...Ch. 4 - In Drosophila, an X-linked recessive mutation,...Ch. 4 - Another recessive mutation in Drosophila, ebony...Ch. 4 - In Drosophila, the X-linked recessive mutation...Ch. 4 - While vermilion is X-linked in Drosophila and...Ch. 4 - In a cross in Drosophila involving the X-linked...Ch. 4 - Consider the three pedigrees below, all involving...Ch. 4 - In goats, the development of the beard is due to a...Ch. 4 - Predict the F1 and F2 results of crossing a male...Ch. 4 - Two mothers give birth to sons at the same time at...Ch. 4 - Discuss the topic of phenotypic expression and the...Ch. 4 - Prob. 35PDQCh. 4 - Labrador retrievers may be black, brown...Ch. 4 - A true-breeding purple-leafed plant isolated from...Ch. 4 - In Dexter and Kerry cattle, animals may be polled...Ch. 4 - A geneticist from an alien planet that prohibits...Ch. 4 - The following pedigree is characteristic of an...Ch. 4 - Students taking a genetics exam were expected to...Ch. 4 - In four oclock plants, many flower colors are...Ch. 4 - Below is a partial pedigree of hemophilia in the...
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- Three recessive mutations in Drosophila melanogaster, roughoid (ru, small rough eyes), javelin (jv, cylindrical bristles), and sepia eyes (se, dark brown eyes) are linked. A three-point cross was carried out and the following progeny obtained: jv+ ru+ se+ 37 jv+ ru+ se 2 jv+ ru se 14 jv+ ru se+ 146 jv ru se+ 2 jv ru se 35 jv ru+ se 154 jv ru+ se+ 10 a. Determine the order of the genes on the chromosome. b. Determine which progeny contain single crossovers and which contain double crossovers and indicate where among the genes the crossovers occurred. c. Calculate the map distances among the genes. d. Calculate the coefficient of coincidence and interference among the genesarrow_forwardIn Drosophila, an X-linked recessive mutation, Xm causes miniature wings. List the F2 phenotypic ratios if: a miniature-winged female is crossed with a normal male and a miniature-winged male is crossed with a normal female. What would the phenotypic ratio from (a) be if the miniature-winged gene were autosomal? Assume in all cases that the P1 individuals are true-breeding.arrow_forwardMiniature wings (Xm) in Drosophila result from an X-linked allele that is recessive to the allele for long wings (X*). Give the genotypes of the parents in the following cross: Male parent Female parent Male offspring Female offspring 231 long, 250 miniature Long Long 560 long O male: Xm/Y and female X* /X* male: X* / Y and female Xm /x O male: X* /Y and female X* /X* male: Xm/Y and female Xm /x+arrow_forward
- Black body (b) and purple eye (pr) are recessive autosomal mutations in Drosophila. Bridges are crossed b/b females with pr/pr males and in the F2 observed 684 wild type, 371 black-bodied, and 300 purple-eyed flies. Do these results indicate that the b and pr genes are closely linked? Explain. (Remember that there is no crossing-over in male Drosophila)..arrow_forwardA standard three-point mapping is conducted for recessive mutations in autosomal genes purple eye (pr), curved wing ( c) and black body (b). Their wild type alleles are also used for genetic mapping. An F1 Drosophila female heterozygous for purple eye (pr), curved wing (c) and black (b) is crossed to a triply homozygous mutant male. The observed numbers and phenotypes of the offspring are as follows: 360 pr c b 380 pr+ c+ b+ 104 pr c+ b 96 pr+ c b+ 30 pr c b+ 20 pr+ c+ b 6 pr c+ b+ 4 pr+ c b PROVIDE THE FOLLOWING: A) State the order of genes on this chromosome. B) Calculate map distances between the gene pairs: pr-c, pr-b, c-b. Show calculations, state the number of map units and which gene pairs they refer to.arrow_forwardThe phenotype of vestigial (short) wings (vg) in Drosophila melanogaster is caused by a recessive mutant gene that independently assorts with a recessive gene for hairy (h) body. Assume that a cross is made between a fly that is homozygous for normal wings and has a hairy body and a fly with vestigial wings that is homozygous for normal body. The wild-type F1 flies were crossed among each other to produce 1024 F2 offspring. Which phenotypes would you expect among the F2 offspring, and how many of each phenotype would you expect? Group of answer choices 192 wild type, 256 vestigial, 64 hairy, and 192 vestigial and hairy All vestigial and hairy. 576 wild type, 192 vestigial, 192 hairy, and 64 vestigial and hairy All wild type 256 wild type; 256 vestigial, 256 hairy, and 256 vestigial and hairyarrow_forward
- In Drosophila fruit flies, the genes for warped wings (dwp), rumpled bristles (rmp), and pallid wings (pld) are linked. A trihybrid female for all three allleles is crossed with homozygous recessive male for all three alleles and the offspring obtained showed the following phenotypes: 3 pld rmp dwp 428 pld rmp + 427 + + dwp 48 + rmp + 47 pld + dwp 23 pld + + 2 + + + 22 + rmp dwp What is the order and map distance between these three alleles?arrow_forwardMiniature wings in Drosophila result from an X-linked allele (w) that is recessive to the allele for long wings (+). In a cross of a long winged male with a long winged female, the following offspring were obtained: 100 long winged males, 106 miniature winged males, and 480 long winged females. Given this result, the female must be a carrier of the miniature wing allele. True Falsearrow_forwardA mutant sex-linked trait called “notched” (N) is deadly in Drosophila when homozygous in females. Males who have a single N allele will also die. The heterozygous condition (Nn) causes small notches on the wing. The normal condition in both male and females is represented by the allele n. a) Indicate the phenotypes of the F1 generation from the following cross: XNXn x XnY b) Explain why dead females are never found in the F1 generation no matter which parents are crossed. c) Explain why the mating of female XNXn and a male XNy is unlikely.arrow_forward
- In Drosophila, an autosomal gene determines the shape of the hair, with B giving straight and b giving bent hairs. On another autosome, there is a gene of which a dominant allele I inhibits hair formation so that the fly is hairless (i has no known phenotypic effect).a. If a straight-haired fly from a pure line is crossed with a fly from a pure-breeding hairless line known to be an inhibited bent genotype, what will the genotypes and phenotypes of the F1 and the F2 be?b. What cross would give the ratio 4 hairless:3 straight:1 bent?arrow_forwardIn Drosophila, the gene for wing type is known to be autosomal with vestigial wings (vg) known to the recessive to normal, long wings (+). You are already familiar with the white eye gene (w) from lecture with the normal color being red (+). Answer the following questions assuming an initial cross (P1) between a pure breeding white eyed, long winged female and a pure breeding red eyed vestigial winged male. a) What are the parental genotypes? b) What phenotypes would occur in the F1 generation and in what proportions? c) What would the phenotypes and phenotypic ratios would occur in F2 generation?arrow_forwardProduce a Punnett square to illustrate the dihybrid cross described below: There are two common alleles for the TAS2R38 gene on Chromosome 7. This gene encodes a seven-transmembrane G-protein coupled receptor. This receptor controls the ability to taste glucosinolates. Phenylthiocarbamide (PTC) is a synthetic glucosinolate. The recessive TAS2R38 allele produces a non-functional receptor. The father in this dihybrid cross is heterozygous for these alleles, meaning that he can taste PTC. The mother is homozygous recessive, meaning that she cannot taste PTC The father has X-Linked Protoporphyria which means that he is very sensitive to sunlight exposure, he is hemizygous for the dominant causative mutation. The mother is homozygous wild type at the same locus. Add a file here showing your diagram.arrow_forward
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