Concepts of Genetics (11th Edition)
11th Edition
ISBN: 9780321948915
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 4, Problem 30PDQ
Consider the three pedigrees below, all involving a single human trait.
- (a) Which combination of conditions, if any, can be excluded?
dominant and X-linked
dominant and autosomal
recessive and X-linked
recessive and autosomal
- (b) For each combination that you excluded, indicate the single individual in generation II (e.g., II-1, II-2) that was most instrumental in your decision to exclude it. If none were excluded, answer “none apply.”
- (c) Given your conclusions in part (a), indicate the genotype of the following individuals:
II-1, II-6, II-9
If more than one possibility applies, list all possibilities. Use the symbols A and a for the genotypes.
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Students have asked these similar questions
The following pedigree shows the inheritance of a human disorder. Affected individuals are
shown with filled symbols.
II
III
2 3
5
Based on the pedigree, propose the least likely inheritance pattern of the disease among
autosomal dominance, autosomal recessive, X-linked dominance and X-linked recessive.
Your choice of answer can be impossible and possible. Explain your answer by giving the
evidence that supports or opposes each mode of inheritance. You can reconstruct the table
shown below and draw the pedigree in your answer script. Write the possible genotype of
each individual in the pedigree for each inheritance pattern proposed.
Mode of
Possibility
Explanations
Pedigree
inheritance
Autosomal
dominance
Autosomal
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X-linked
dominance
X-linked
recessive
Look at the pedigree below and answer the following questions related to the human genetic trait depicted in this pedigree.
1. Indicate whether the pattern of inheritance associated with this human trait is most likely to be (i) rare X-linked recessive, (ii) sex-influenced, or (iii) sex-limited. You may assume that the gene is fully penetrant.
Then, provide a specific reason that justifies your selection of this pattern of inheritance as the correct one, and also explain why each of the other two alternatives are not correct. As part of your answer, include the phenotypic ratio, including the sex of the offspring, that you would expect to find in each of the three possible scenarios.
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(a)
(b)
II
1
Chapter 4 Solutions
Concepts of Genetics (11th Edition)
Ch. 4 - In the guinea pig, one locus involved in the...Ch. 4 - In some plants a red flower pigment, cyanidin, is...Ch. 4 - Below are three pedigrees. For each trait,...Ch. 4 - Prob. 1CSCh. 4 - Prob. 2CSCh. 4 - Prob. 3CSCh. 4 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 4 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 4 - In shorthorn cattle, coat color may be red, white,...Ch. 4 - In foxes, two alleles of a single gene, P and p,...
Ch. 4 - In mice, a short-tailed mutant was discovered....Ch. 4 - List all possible genotypes for the A, B, AB, and...Ch. 4 - With regard to the ABO blood types in humans,...Ch. 4 - In a disputed parentage case, the child is blood...Ch. 4 - The A and B antigens in humans may be found in...Ch. 4 - In chickens, a condition referred to as creeper...Ch. 4 - In rabbits, a series of multiple alleles controls...Ch. 4 - Three gene pairs located on separate autosomes...Ch. 4 - As in Problem 12, flower color may be red, white,...Ch. 4 - Horses can be cremello (a light cream color),...Ch. 4 - With reference to the eye color phenotypes...Ch. 4 - Pigment in mouse fur is only produced when the C...Ch. 4 - In rats, the following genotypes of two...Ch. 4 - Given the inheritance pattern of coat color in...Ch. 4 - In a species of the cat family, eye color can be...Ch. 4 - In a plant, a tall variety was crossed with a...Ch. 4 - In a unique species of plants, flowers may be...Ch. 4 - Five human matings (15), identified by both...Ch. 4 - A husband and wife have normal vision, although...Ch. 4 - In humans, the ABO blood type is under the control...Ch. 4 - In Drosophila, an X-linked recessive mutation,...Ch. 4 - Another recessive mutation in Drosophila, ebony...Ch. 4 - In Drosophila, the X-linked recessive mutation...Ch. 4 - While vermilion is X-linked in Drosophila and...Ch. 4 - In a cross in Drosophila involving the X-linked...Ch. 4 - Consider the three pedigrees below, all involving...Ch. 4 - In goats, the development of the beard is due to a...Ch. 4 - Predict the F1 and F2 results of crossing a male...Ch. 4 - Two mothers give birth to sons at the same time at...Ch. 4 - Discuss the topic of phenotypic expression and the...Ch. 4 - Prob. 35PDQCh. 4 - Labrador retrievers may be black, brown...Ch. 4 - A true-breeding purple-leafed plant isolated from...Ch. 4 - In Dexter and Kerry cattle, animals may be polled...Ch. 4 - A geneticist from an alien planet that prohibits...Ch. 4 - The following pedigree is characteristic of an...Ch. 4 - Students taking a genetics exam were expected to...Ch. 4 - In four oclock plants, many flower colors are...Ch. 4 - Proto-oncogenes stimulate cells to progress...Ch. 4 - Below is a partial pedigree of hemophilia in the...
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