Prescott's Microbiology
Prescott's Microbiology
10th Edition
ISBN: 9781259281594
Author: Joanne Willey, Linda Sherwood Adjunt Professor Lecturer, Christopher J. Woolverton Professor
Publisher: McGraw-Hill Education
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Chapter 38, Problem 9CHI
Summary Introduction

To determine: The features of a specific type of viral infection that drive the evolution of the virus, and give reasons to support the answer.

Introduction: In nature, more than 400 different viruses are present that can infect humans. The viruses are categorized based on their mode of transmission and acquisition. Examples of viral diseases are Ebola hemorrhagic fever, hantavirus pulmonary syndrome, and influenza.

Summary Introduction

To determine: An example to show that infection of epithelial cells would be favored over the infection of neurons.

Introduction: In nature, more than 400 different viruses are present that can infect humans. The viruses are categorized based on their mode of transmission and acquisition. Examples of viral diseases are Ebola hemorrhagic fever, hantavirus pulmonary syndrome, and influenza.

Summary Introduction

To suggest: A mechanism that could be used by RNA viruses to enhance the infectivity by risking the extinction.

Introduction: In nature, more than 400 different viruses are present that can infect humans. The viruses are categorized based on their mode of transmission and acquisition. Examples of viral diseases are Ebola hemorrhagic fever, hantavirus pulmonary syndrome, and influenza.

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Some retroviruses that have a wide host range have been developed for use in treatment of diseases or syndromes. These viruses do not result in a productive infection because they lack critical genes for viral replication, but they do carry DNA sequences that allow them to be packaged into infectious particles. Once in the host cell the viral DNA is released and integrates into the cell's genome. The advantage to this strategy is that the delivery of the DNA is very efficient. What is one possible problem of using a virus that can integrate into the human nuclear genome? Multiple Choice The virus carries genes that will interfere with host cell activities. The viral DNA sequences could still cause a disease. Since the viral DNA sequences no longer contain essential genes for viral replication the host cell may not be able to replicate either. The integration could disrupt an essential gene or genes.
Coronaviridae is a virus “family.” There are actually many different coronaviruses within this group, including less pathogenic virus strains that cause the common cold. Many people in this course have likely been infected with one of these other coronaviruses. A common feature of coronaviruses and other RNA viruses (think influenza virus, HIV, etc.) is that they mutate frequently. This is because the viral enzymes that copy the genome during replication can’t fix mistakes. Given this information, how might we be able to distinguish the SARS-CoV-2 strain from some of the other, less concerning, coronavirus strains?
Viruses are made up of the same biomolecules as cellular organisms (DNA, RNA, proteins, lipids, etc.), which are synthesized through enzymatic dehydration reactions from building blocks and disassembled by enzymatic hydrolysis. They infect cells and replicate themselves using resources from the host cells. Scientists discovered a previously unknown strain of virus in the tropical Pacific Ocean and it can infect higher-order eukaryotes. Initial analysis revealed that the virus is mainly composed of nucleic acids, proteins, and lipids. Chemical analysis after complete hydrolysis revealed the following building blocks (by weight): Chemical components Nucleosides Amino acids Lipids, phosphates, and carbohydrates Percentage by weight 20 30 50 Analysis of percentages of nucleosides yielded the following results (by molar ratio): Nucleosides A G T C U Percentage by mole 19 29 19 29 4 Which of the following events mostly involves hydrolysis reaction after the virus infects…
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