Chapter 37, Problem 13A

Summary Introduction

To determine:

The virus in cell cultures would be an exception to Koch postulate.

Introduction :

Robert Koch experimented on mouse that how a particular bacteria was causing an infectious disease.

Explanation of Solution

In the experiment he injected healthy mice with a material from diseased animals, and the mice became ill. After transferring anthrax by inoculation through a series of 20 mice, he incubated a piece of spleen containing the anthrax bacillus in beef serum then the bacilli grew, reproduced, and produced spores and when the isolated bacilli or spores were injected into mice and anthrax developed. During his studies on bacterial diseases, it became necessary to isolate suspected bacterial pathogens. Thus, his criteria for proving the causal relationship between a microorganism and a specific disease are known as Koch’s postulates.