EBK SEELEY'S ANATOMY & PHYSIOLOGY
11th Edition
ISBN: 9781259671166
Author: VanPutte
Publisher: MCGRAW HILL BOOK COMPANY
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Chapter 3.5, Problem 18AYP
Summary Introduction
To analyze:
The part of a receptor molecule at which a chemical signal is attached. Also, determine the ways by which a chemical signal can bind to a receptor on a channel protein.
Introduction:
The receptor proteins are the membrane proteins that have an exposed receptor site present on the outer cell surface. The receptor proteins are also known as glycoproteins. The chemical signal attaches to the receptor site.
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Separately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item (a, b, c, or d) best represents the forces and fluxes for a membrane potential of +20 mV? Upwards arrows means outward direction and downwards arrow means inward direction. The length of the arrow determines the magnitude.
Describe how activation of a receptor channel produces a cellular response.
Ligand binding of a (????) causes conformational changes in the receptor that free the associated G-protein to interact with other membrane proteins
Voltage gated ion channel
GPCR
Ligand gated ion channel
Ligandase pore
Chapter 3 Solutions
EBK SEELEY'S ANATOMY & PHYSIOLOGY
Ch. 3.1 - What parts are common to most cells?Ch. 3.1 - Explain the four characteristic functions of the...Ch. 3.2 - Which cell features can be seen with a light...Ch. 3.3 - Explain five functions of the plasma membrane.Ch. 3.3 - Prob. 5AYPCh. 3.3 - Prob. 6AYPCh. 3.3 - What are the main chemical components of the...Ch. 3.4 - Prob. 8AYPCh. 3.4 - Summarize the characteristics of the fluid-mosaic...Ch. 3.4 - Prob. 10AYP
Ch. 3.5 - Prob. 11AYPCh. 3.5 - Prob. 12AYPCh. 3.5 - What are the three classes of transport proteins?Ch. 3.5 - Describe specificity, competition, and saturation...Ch. 3.5 - Prob. 15AYPCh. 3.5 - Prob. 16AYPCh. 3.5 - Prob. 17AYPCh. 3.5 - Prob. 18AYPCh. 3.5 - Prob. 19AYPCh. 3.5 - Prob. 20AYPCh. 3.6 - Explain why the plasma membrane is selectively...Ch. 3.6 - Prob. 22AYPCh. 3.6 - Describe how the amount of solute in a solvent...Ch. 3.6 - How is the rate of diffusion affected by an...Ch. 3.6 - Prob. 25AYPCh. 3.6 - Compare isosmotic, hyperosmotic, and hyposmotic...Ch. 3.6 - Prob. 27AYPCh. 3.6 - Prob. 28AYPCh. 3.6 - What is secondary active transport? Describe how...Ch. 3.6 - Prob. 30AYPCh. 3.6 - Prob. 31AYPCh. 3.6 - Prob. 32AYPCh. 3.6 - Describe and give examples of exocytosis.Ch. 3.7 - Prob. 34AYPCh. 3.7 - Prob. 35AYPCh. 3.7 - List and describe the functions of microtubules,...Ch. 3.7 - What are cytoplasmic inclusions? Give several...Ch. 3.8 - Define organelles. Are oil orgonelles found in oil...Ch. 3.8 - Describe the structure of the nucleus and the...Ch. 3.8 - Prob. 40AYPCh. 3.8 - Prob. 41AYPCh. 3.8 - Prob. 42AYPCh. 3.8 - What molecules combine to form ribosomes? Where...Ch. 3.8 - Prob. 44AYPCh. 3.8 - Prob. 45AYPCh. 3.8 - What are the functions of the rough endoplasmic...Ch. 3.8 - Prob. 47AYPCh. 3.8 - Relate the structure and function of the Golgi...Ch. 3.8 - Prob. 49AYPCh. 3.8 - Prob. 50AYPCh. 3.8 - Prob. 51AYPCh. 3.8 - Prob. 52AYPCh. 3.8 - What are the structure and function of...Ch. 3.8 - Describe the structure of a mitochondrion. How...Ch. 3.8 - What enzymes are found on the cristae? In the...Ch. 3.8 - What is the centrosome? Relate the structure of...Ch. 3.8 - What are spindle fibers? Explain the relationship...Ch. 3.8 - Prob. 58AYPCh. 3.8 - Prob. 59AYPCh. 3.9 - Prob. 60AYPCh. 3.9 - Prob. 61AYPCh. 3.9 - Prob. 62AYPCh. 3.9 - Prob. 63AYPCh. 3.9 - Prob. 64AYPCh. 3.9 - Prob. 65AYPCh. 3.9 - Prob. 66AYPCh. 3.9 - Place the steps of translation in sequence. In...Ch. 3.9 - Prob. 68AYPCh. 3.9 - State two ways the cell controls what part of DNA...Ch. 3.10 - Describe the cell’s activities during the G1, S....Ch. 3.10 - Prob. 71AYPCh. 3.10 - Prob. 72AYPCh. 3.10 - Prob. 73AYPCh. 3.10 - Differentiate among chromot in, chromcitids, and...Ch. 3.10 - Prob. 75AYPCh. 3.10 - Prob. 76AYPCh. 3.10 - Prob. 77AYPCh. 3.11 - Prob. 78AYPCh. 3 - In the plasma membrane, _____ form(s) the lipid...Ch. 3 - Which of the following functioning proteins are...Ch. 3 - In general, lipid-soluble molecules diffuse...Ch. 3 - Small pieces of matter, and even whole cells, can...Ch. 3 - The rate of diffusion increases if the a....Ch. 3 - Concerning the process of diffusion, at...Ch. 3 - Prob. 7RACCh. 3 - Prob. 8RACCh. 3 - Which of these statements about facilitated...Ch. 3 - Which of these statements concerning the symport...Ch. 3 - A white blood cell ingests solid particles by...Ch. 3 - Given these characteristics: (1) requires energy...Ch. 3 - Cytoplasm is found a. in the nucleus. b. outside...Ch. 3 - Which of these elements of the cytoskeleton is...Ch. 3 - A large structure, normally visible in the nucleus...Ch. 3 - A cell that synthesizes large amounts of protein...Ch. 3 - Which of thes organelles produces large amounts of...Ch. 3 - Prob. 18RACCh. 3 - A portion of an mRNA molecule that determines one...Ch. 3 - In which of these organelles is m RNA synthesized?...Ch. 3 - During the cell cycle, DNA replication occurs...Ch. 3 - Given the following activities: Repair Growht...Ch. 3 - Apoptosis Is a programmed cell death. Removes...Ch. 3 - Prob. 1CTCh. 3 - Prob. 2CTCh. 3 - Prob. 3CTCh. 3 - Prob. 4CTCh. 3 - Luke started a training program at the beginning...Ch. 3 - Prob. 6CT
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- Which statement best describes the interaction that occurs as a result of the binding of a ligand to a ligand-gated ion channel receptor? A B с D ligand extracellular environment gate closed inactive ligand-gated ion channel receptor ions The process permanently opens or closes the ion channel. cytoplasm The process alters the membrane potential by changing the intracellular ionic concentration. The process causes G proteins to bind with GTP and become activated. The process removes three sodium ions from the cell and brings in two potassium ions.arrow_forwardDraw a sketch of a graph showing a complex AHP consisting of a first component AHP, an ADP, and a second component AHP before repolarization to resting membrane potentialarrow_forwardSeparately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item best represents the forces and fluxes for a membrane potential of 0 mV?arrow_forward
- What type of ion channel contributes to the restingmembrane potential? Describe the permeabilitycharacteristics of the plasma membrane.arrow_forwardMembrane channels and carriers both show changes in protein conformation. What is the role of such conformation changes in: (1) channels, and (2) carriers?arrow_forwardSeparately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item best represents the forces and fluxes for a membrane potential of -60 mV?arrow_forward
- Separately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item best represents the forces and fluxes for a membrane potential of -40 mV (a, b, c, or d)? Upwards arrows means outward direction and downwards arrow means inward direction. The length of the arrow determines the magnitude.arrow_forwardSeparately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item best represents the forces and fluxes for a membrane potential of -20 mV?arrow_forwardSeparately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item best represents the forces and fluxes for a membrane potential of -40 mV?arrow_forward
- Explain why this is not true about ion channel receptors; It forms hydrophobic hollow because it is a membrane bound receptor.arrow_forwardWhat properties of ion channels allow them to generate the large, rapid changes in membrane potential?arrow_forwardYou perform a competition study on a GPCR. You have isolated the plasma membrane from cells which contains the GPCR of interest. If an agonist and an inverse agonist are at equal concentrations in your study but the inverse agonist has a 10 x higher affinity for the receptor than the agonist, what would you expect to be the overall outcome to be? More of the agonist is bound and so most of the receptor is in its active conformation and is stimulated More of the inverse agonist is bound and so most of the receptor is in its inactive conformation and is unstimulated.arrow_forward
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