Chapter 33, Problem 35A

Summary Introduction

To discuss: the consequences that might arise if a person’s gene for production of dopamine was defective.

Introduction:- Dopamine is a neurotransmitter that plays a significant function in both the body and brain. Five genes of significance are located in dopamine. It is a dopamine transport protein (DAT) that controls synaptic dopamine levels and dopamine receptors (D1, D2, and D3).

These five proteins are commonly divulged in the brain: cortex and basal ganglia are located in DRD1 and DRD2.

Explanation of Solution

Dopamine plays an important role in regulating a person's actions and emotional reactions. Dopamine’s right balance is important for both physical and mental health.

Consequences that might arise if a gene for dopamine production is defective:-

• Defective dopamine may lead to mental disorders like Bipolar disorder, ADHD, Alzheimer's, Parkinson's, depression. Vital brain functions such as sleep, mood, memory, learning, attention, and motor controlled by dopamine levels in a person's body.
• Lack of dopamine genes may lead to Gastroesophageal reflux (GERD) disease; Frequent Pneumonia outbursts and sleeping disorders
• Dopamine is a neurotransmitter, which controls communication in the brain. These neurons are responsible for a significant amount of body motor regulation. The death of dopaminergic neurons results in Parkinson's disease symptoms — tremor, rigidity, and lack of voluntary movement.
• Defective dopamine genes lead to mental retardation.