Concept explainers
To discuss:
The distinction between leak channels and gated channels, and between ligand-gated, voltage-gated and mechanically gated channels.
Introduction:
Cells are regarded as the simplest unit (structural and functional) of life. Cellular membrane, nucleus, and cytoplasm are the three major components of a cell. Cellular membrane, which surrounds the entire cell, is composed of phospholipids and proteins. Membrane proteins that traverse the entire cell membrane alone can serve as a membrane channel. A channel protein aids in the transfer of solutes (water and hydrophilic solutes) from one side of the selectively permeable membrane to the other side of the membrane. Such integral proteins are called as transmembrane proteins.

Want to see the full answer?
Check out a sample textbook solution
Chapter 3 Solutions
Anatomy and Physiology
- 22. Which of the following mutant proteins is expected to have a dominant negative effect when over- expressed in normal cells? a. mutant PI3-kinase that lacks the SH2 domain but retains the kinase function b. mutant Grb2 protein that cannot bind to RTK c. mutant RTK that lacks the extracellular domain d. mutant PDK that has the PH domain but lost the kinase function e. all of the abovearrow_forwardWhat is the label ?arrow_forwardCan you described the image? Can you explain the question as well their answer and how to get to an answer to an problem like this?arrow_forward
- Describe the principle of homeostasis.arrow_forwardExplain how the hormones of the glands listed below travel around the body to target organs and tissues : Pituitary gland Hypothalamus Thyroid Parathyroid Adrenal Pineal Pancreas(islets of langerhans) Gonads (testes and ovaries) Placentaarrow_forwardWhat are the functions of the hormones produced in the glands listed below: Pituitary gland Hypothalamus Thyroid Parathyroid Adrenal Pineal Pancreas(islets of langerhans) Gonads (testes and ovaries) Placentaarrow_forward
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage LearningHuman Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage LearningAnatomy & PhysiologyBiologyISBN:9781938168130Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark WomblePublisher:OpenStax College
- Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxBiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning




