The mechanism for the given reaction is to be drawn. Concept introduction: In biological reactions, allylic carbocations are the intermediates that are required for the formation of Farnesyl diphosphate. The general steps involved in the biological formation of Farnesyl diphosphate are stated below. ➢ The first step is the generation of allylic carbocation by the loss of the diphosphate group. ➢ The second step is the nucleophilic attack of isopentyl diphosphate to form new bond. ➢ The third step is the deprotonation to give final product.

Question

(a 4 shows scanning electron microscope (SEM) images of extruded actions of packing bed for two capillary columns of different diameters, al 750 (bottom image) and b) 30-μm-i.d. Both columns are packed with the same stationary phase, spherical particles with 1-um diameter. A) When the columns were prepared, the figure shows that the column with the larger diameter has more packing irregularities. Explain this observation. B) Predict what affect this should have on band broadening and discuss your prediction using the van Deemter terms. C) Does this figure support your explanations in application question 33? Explain why or why not and make any changes in your answers in light of this figure. Figure 4 SEM images of sections of packed columns for a) 750 and b) 30-um-i.d. capillary columns.³

Answer 1

Question

Chapter 31, Problem 31.41P

Interpretation Introduction

Interpretation: The mechanism for the given reaction is to be drawn.

Concept introduction: In biological reactions, allylic carbocations are the intermediates that are required for the formation of Farnesyl diphosphate.

The general steps involved in the biological formation of Farnesyl diphosphate are stated below.

➢ The first step is the generation of allylic carbocation by the loss of the diphosphate group.

➢ The second step is the nucleophilic attack of isopentyl diphosphate to form new bond.

➢ The third step is the deprotonation to give final product.

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